Rheumatoid arthritis (RA) is a chronic immune-mediated disease that primarily affects the
synovium of diarthrodial joints. During the course of RA, the synovium transforms into a …

Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …

Innate immune cells have complex signalling pathways for sensing pathogens and initiating
innate immune responses against infection. These pathways are tightly regulated at different …

An increasing number of studies show how changes in intracellular metabolic pathways
alter tumor and immune cell function. However, little information about metabolic changes in …

Polyamines (ie, putrescine, spermidine, and spermine) are bioactive polycations capable of
binding nucleic acids and proteins and modulating signaling pathways. Polyamine functions …

Studies have found that neutrophil extracellular traps (NETs) which are the specific dying
form of neutrophil upon activation have fundamental role in the rheumatoid arthritis onset …

Despite improvements in modern medical therapies, inflammatory diseases, such as
atherosclerosis, diabetes, non-alcoholic fatty liver, chronic kidney diseases, and …

(1) Background: Marine n-3 polyunsaturated fatty acids (PUFA) and ɤ-linolenic acid (GLA)
are well-known anti-inflammatory agents that may help in the treatment of inflammatory …