Over the years, Friedel–Crafts (FC) reactions have been acknowledged as the most useful
and powerful synthetic tools for the construction of a special kind of carbon–carbon bond …

The pseudoindoxyl sub-structural motif, amongst the large set of the indole class of
alkaloids, represents a unique subset of the oxygenated indole class of the alkaloid family. A …

Enantioselective total syntheses of title natural products from a common cyclohexenone
derivative (S)-18 were reported. Ozonolysis of (S)-18 afforded a stable diketo ester (R)-17 …

Inspired by their potential biosynthesis, we have developed divergent total syntheses of
seven monoterpene indole alkaloids including mersicarpine, leuconodines B and D …

Herein we report a branch-selective allylation strategy for accessing C2-indolyl-all-carbon
quaternary centers using allylboronic acids. This approach boasts broad functional group …

Intramolecular homolytic aromatic silylation of biphenyl-2-hydrosilanes via silyl radicals has
been developed for the synthesis of silafluorenes. Moreover, silaindenes are synthesized …

Total syntheses of leuconodine B, melodinine E, and leuconoxine were accomplished via a
divergent route. The [5.5. 6.6] diazafenestrane skeleton was constructed from an indole-3 …

Because of their unique molecular architecture, the manzacidins have been the subject of
intense synthetic efforts in the past two decades. Here, we describe two synthetic …

The application of the DMSO/SOCl2 system enabled the intramolecular
cyclization/chlorination of N, N-disubstituted 2-alkynylanilines, leading to the synthesis of a …

The Aspidosperma alkaloids leuconoxine, melodinine E, and mersicarpine were
synthesized. The approach features a key cascade radical reaction. A 1, 5‐hydrogen atom …