Non-targeted effects (NTE) have been generally regarded as a low-dose ionizing radiation
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …

This review summarises our current understanding of the radiation-induced
bystander/systemic effect (RIBE) as well as other types of intercellular reactions induced by …

Abstract Background Cancer-associated fibroblasts (CAFs) are a major component of the
cancer stroma, and their response to therapeutic treatments likely impacts the outcome. We …

Radiation therapy is an effective cancer therapy, but damage to normal tissues surrounding
the tumor due to radiotherapy causes severe complications. The importance of the …

Purpose The assumption that traversal of the cell nucleus by ionizing radiation is a
prerequisite to induce genetic damage, or other important biological responses, has been …

Nowadays, using ionizing radiation (IR) is necessary for clinical, agricultural, nuclear energy
or industrial applications. Accidental exposure to IR after a radiation terror or disaster poses …

In vitro and in vivo observations accumulated over several decades have firmly shown that
the biological effects of ionizing radiation can spread from irradiated cells/tissues to non …

Radiation-induced bystander effects have been implicated in contributing to the growth
delay of disseminated tumor cells (DTC) caused by 223RaCl2, an alpha particle–emitting …

The increasing use of ionizing radiation (IR) in medical diagnosis and treatment has caused
considerable concern regarding the effects of occupational exposure on human health …

Redox modulated pathways play important roles in out-of-field effects of ionizing radiation.
We investigated how the redox environment impacts the magnitude of propagation of …