Molecular and cellular mechanisms linking air pollution and bone damage
D Prada, G López, H Solleiro-Villavicencio… - Environmental …, 2020 - Elsevier
Air pollution is the second most important risk factor associated with noncommunicable
diseases after smoking. The effects of pollution on health are commonly attributable to …
diseases after smoking. The effects of pollution on health are commonly attributable to …
The aryl hydrocarbon receptor has a normal function in the regulation of hematopoietic and other stem/progenitor cell populations
The aryl hydrocarbon receptor (AhR) is known mainly as the mediator for the toxicity of
certain xenobiotics. However, there is also much information to indicate that this transcription …
certain xenobiotics. However, there is also much information to indicate that this transcription …
The highly potent AhR agonist picoberin modulates Hh-dependent osteoblast differentiation
J Flegel, S Shaaban, ZJ Jia, B Schulte… - Journal of Medicinal …, 2022 - ACS Publications
Identification and analysis of small molecule bioactivity in target-agnostic cellular assays
and monitoring changes in phenotype followed by identification of the biological target are a …
and monitoring changes in phenotype followed by identification of the biological target are a …
Heavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signaling
Background: Exposure to lead (Pb) from environmental and industrial sources remains an
overlooked serious public health risk. Elucidating the effect of Pb on bone cell function is …
overlooked serious public health risk. Elucidating the effect of Pb on bone cell function is …
A novel quercetin analogue from a medicinal plant promotes peak bone mass achievement and bone healing after injury and exerts an anabolic effect on osteoporotic …
We recently reported that extracts made from the stem bark of Ulmus wallichiana promoted
peak bone mass achievement in growing rats and preserved trabecular bone mass and …
peak bone mass achievement in growing rats and preserved trabecular bone mass and …
Dioxins interfere with differentiation of osteoblasts and osteoclasts
M Korkalainen, E Kallio, A Olkku, K Nelo, J Ilvesaro… - Bone, 2009 - Elsevier
We have previously shown that the environmental contaminant 2, 3, 7, 8-tetrachlorodibenzo-
p-dioxin (TCDD) affects bone growth, modelling and mechanical strength in vivo. In this …
p-dioxin (TCDD) affects bone growth, modelling and mechanical strength in vivo. In this …
Osteo-transcriptomics of human mesenchymal stem cells: accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an …
E Piek, LS Sleumer, EP van Someren, L Heuver… - Bone, 2010 - Elsevier
Bone marrow-derived human mesenchymal stem cells (hMSCs) have the in vitro capacity to
differentiate into osteoblasts, chondrocytes or adipocytes, depending on the applied …
differentiate into osteoblasts, chondrocytes or adipocytes, depending on the applied …
Surface characteristics and biocompatibility of sandblasted and acid‐etched titanium surface modified by ultraviolet irradiation: An in vitro study
S Li, J Ni, X Liu, X Zhang, S Yin, M Rong… - … Research Part B …, 2012 - Wiley Online Library
Sandblasting with large grit and acid‐etching (SLA) treatment is considered to be a reliable
modification to achieve excellent titanium surface. However, contamination of hydrocarbons …
modification to achieve excellent titanium surface. However, contamination of hydrocarbons …
Bone and bone marrow disruption by endocrine‐active substances
D Agas, G Lacava, MG Sabbieti - Journal of cellular physiology, 2019 - Wiley Online Library
Bone is a multifaceted dynamic tissue, involved in mobility, mineral metabolism, and
mesenchymal or stromal and hematopoietic progenitor or stem cells breading. Recently, an …
mesenchymal or stromal and hematopoietic progenitor or stem cells breading. Recently, an …
Effects of combined exposure to lead and high-fat diet on bone quality in juvenile male mice
EE Beier, JA Inzana, TJ Sheu, L Shu… - Environmental …, 2015 - ehp.niehs.nih.gov
Background Lead (Pb) exposure and obesity are co-occurring risk factors for decreased
bone mass in the young, particularly in low socioeconomic communities. Objectives The …
bone mass in the young, particularly in low socioeconomic communities. Objectives The …