The selection of antibodies from combinatorial libraries displayed on the surface of
filamentous phage has become an important methodology for the generation of reagent …

Historically, antibody variable domains for therapeutic antibodies have been sourced
primarily from the mouse IgG repertoire, and typically either chimerized or humanized. More …

The book provides a comprehensive view of the impact and promise of phage display in
drug discovery and biotechnology. Building on the success of its previous edition, the book …

Antibodies against the fusion (F) protein of respiratory syncytial virus (RSV) play an
important role in the protective immune response to this important respiratory virus. Little is …

Throughout the last several decades, vaccination has been key to prevent and eradicate
infectious diseases. However, many pathogens (eg, respiratory syncytial virus [RSV] …

A valuable resource for researchers and workers in the fields of both pharmaceuticals and
biotechnology as well as undergraduates in biochemistry, applied biology, biomedical …

Human metapneumovirus (hMPV), a newly discovered paramyxovirus, is associated with
acute respiratory-tract illness, primarily in young children, individuals with underlying …

PCPP, a well-defined polyphosphazene macromolecule, has been studied as an
immunoadjuvant for a soluble form of the postfusion glycoprotein of respiratory syncytial …

Targeting in immunotherapy has traditionally been achieved by using monoclonal rodent
antibodies. Despite gene-engineering, there are many problems and limitations associated …

A humanized monoclonal antibody (mAb) has been developed and its potential to protect
from or cure a Venezuelan equine encephalomyelitis virus (VEEV) infection was evaluated …