The GATA family of transcription factors is of crucial importance during embryonic
development, playing complex and widespread roles in cell fate decisions and tissue …

The reproductive endocrine systems are vastly different between males and females. This
sexual dimorphism of the endocrine milieu originates from sex-specific differentiation of the …

The adrenal cortex undergoes remodeling during fetal and postnatal life. How zona
reticularis emerges in the postnatal gland to support adrenarche, a process whereby higher …

The standard model of adrenocortical zonation holds that the three main zones,
glomerulosa, fasciculata, and reticularis each have a distinct function, producing …

The adrenal cortex is divided into concentric zones. In humans the major cortical zones are
the zona glomerulosa, zona fasciculata, and zona reticularis. The adrenal cortex is a …

In humans, reticularis cells of the adrenal cortex fuel the production of androgen steroids,
constituting the driver of numerous morphological changes during childhood. These steps …

The adrenal gland controls a plethora of crucial physiological functions, and dysfunction is
associated with severe morbidity. Because of the vital importance of appropriate adrenal …

The X-zone is a transient cortical region enriched in eosinophilic cells located in the cortical–
medullary boundary of the mouse adrenal gland. Similar to the X-zone, the fetal zone in …

The adrenal cortex functions to produce steroid hormones necessary for life. To maintain its
functional capacity throughout life, the adrenal cortex must be continually replenished and …

The roles of the GATA4 and GATA6 transcription factors in testis development were
examined by simultaneously ablating Gata4 and Gata6 with Sf1Cre (Nr5a1Cre). The …