Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …

Alzheimer's disease (AD) is the most common neurodegenerative disease illustrated by
neuronal dysfunctions, leading to memory weaknesses and personality changes mostly in …

A deeper understanding of the molecular processes underlying late-onset Alzheimer's
disease (LOAD) could aid in biomarker and drug target discovery. Using high-throughput …

The amyloid cascade is the most frequently accepted hypothesis of Alzheimer's Disease
(AD). According to this hypothesis, the formation of plaques precedes the appearance of …

Sinomenine is a natural compound extracted from the medicinal plant Sinomenium acutum.
Its supplementation has been shown to present benefits in a variety of animal models of …

Alzheimer's disease (AD) is a serious neurodegenerative disease characterized by memory
impairment, mental retardation, impaired motor balance, loss of self-care and even death …

Alzheimer's disease is a progressive neurodegenerative disorder and the most common
cause of dementia that principally affects older adults. Pathogenic factors, such as oxidative …

Intermittent hypoxia (IH), one of the primary pathologies of sleep apnea syndrome (SAS),
exposes cells throughout the body to repeated cycles of hypoxia/normoxia that result in …

Background The accumulation of β-amyloid (Aβ) peptides into insoluble plaques is an early
pathological feature of Alzheimer's disease (AD). BACE1 is the sole β-secretase for Aβ …

Disease-modifying therapies (DMT) for Alzheimer's disease (AD) are highly longed-for. In
this quest, anti-amyloid therapies take center stage supported by genetic facts that highlight …