Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder of unknown etiology.
IBS is caused by a disruption in the gut-brain axis. Given the importance of the gut …

Enterochromaffin (EC) cells constitute the largest population of intestinal epithelial
enteroendocrine (EE) cells. EC cells are proposed to be specialized mechanosensory cells …

Irritable bowel syndrome is a common functional gastrointestinal disorder, and it has been
shown that the etiology of irritable bowel syndrome is a multifactorial complex of …

In recent years, increasing studies have been conducted on the mechanism of gut
microbiota in neuropsychiatric diseases and non-neuropsychiatric diseases. The academic …

Increasing evidence has accumulated that gut microbiome dysbiosis could be linked to
neurological diseases, including both neurodegenerative and psychiatric diseases. With the …

In the gastrointestinal tract, serotonin (5-hydroxytryptamine, 5-HT) is an important
monoamine that regulates intestinal dynamics. QGP-1 cells are human-derived …

Enteroendocrine cells (EECs) are specialized sensors of luminal forces and chemicals in the
gastrointestinal (GI) epithelium that respond to stimulation with a release of signalling …

The gastrointestinal tract constantly communicates with the environment, receiving and
processing a wide range of information. The contents of the gastrointestinal tract and the …

The enteroendocrine cells in gastrointestinal (GI) tract synthesize more than thirty hormones
in mammals. Among these cells, the enterochromaffin (EC) cells are probably the most …