summary Erythrocyte transfusion is essential in conditions of large blood loss, of inadequate
bone marrow production and of increased erythrocyte breakdown. The structural and …

Regulatory T (Treg) cells maintain peripheral tolerance and limit effector responses to
prevent excessive immune-mediated tissue damage. However, recent research reveals that …

Cancer immunotherapy is mainly focused on manipulating patient's own immune system to
recognize and destroy cancer cells. Vaccine formulations based on nanotechnology have …

Regulatory T cells (Tregs) can potentially migrate to the B cell areas of secondary lymphoid
tissues and suppress T cell-dependent B cell Ig response. T cell-dependent Ig response …

BACKGROUND: The development of autoimmune sequelae is one of the characteristic
features of drug reaction with eosinophilia and systemic symptoms (DRESS) or drug …

Autoimmune hemolytic anemia (AIHA) is an uncommon autoantibody-mediated immune
disorder that affects both children and adults. The diagnosis of AIHA relies mainly on the …

The mTOR pathway plays a central role in many cellular processes, such as cellular growth,
protein synthesis, glucose, and lipid metabolism. Aberrant regulation of mTOR is a hallmark …

Autoimmune hemolytic anemia (AIHA) is defined as a condition associated with the
increased destruction of red blood cells (RBCs) associated with the presence of IgG anti …

Autoimmune hemolytic anemia (AIHA) is an acquired, heterogeneous group of diseases
which includes warm AIHA, cold agglutinin disease (CAD), mixed AIHA, paroxysmal cold …

Investigation of the role of regulatory T cells (Treg) in model systems is facilitated by their
depletion using anti-CD25 Abs, but there has been considerable debate about the …