[HTML][HTML] Fusion tags for protein solubility, purification and immunogenicity in Escherichia coli: the novel Fh8 system
Proteins are now widely produced in diverse microbial cell factories. The Escherichia coli is
still the dominant host for recombinant protein production but, as a bacterial cell, it also has …
still the dominant host for recombinant protein production but, as a bacterial cell, it also has …
[HTML][HTML] Stapled peptides inhibitors: a new window for target drug discovery
AM Ali, J Atmaj, N Van Oosterwijk, MR Groves… - Computational and …, 2019 - Elsevier
Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …
[HTML][HTML] Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways
MJ Pichler, C Yamada, B Shuoker… - Nature …, 2020 - nature.com
The early life human gut microbiota exerts life-long health effects on the host, but the
mechanisms underpinning its assembly remain elusive. Particularly, the early colonization of …
mechanisms underpinning its assembly remain elusive. Particularly, the early colonization of …
Enhancement of soluble protein expression through the use of fusion tags
D Esposito, DK Chatterjee - Current opinion in biotechnology, 2006 - Elsevier
The soluble expression of heterologous proteins in Escherichia coli remains a serious
bottleneck in protein production. Although alteration of expression conditions can sometimes …
bottleneck in protein production. Although alteration of expression conditions can sometimes …
Cytokinin signalling inhibitory fields provide robustness to phyllotaxis
How biological systems generate reproducible patterns with high precision is a central
question in science. The shoot apical meristem (SAM), a specialized tissue producing plant …
question in science. The shoot apical meristem (SAM), a specialized tissue producing plant …
Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut
Metabolism of dietary glycans is pivotal in shaping the human gut microbiota. However, the
mechanisms that promote competition for glycans among gut commensals remain unclear …
mechanisms that promote competition for glycans among gut commensals remain unclear …
The F-box protein UFO controls flower development by redirecting the master transcription factor LEAFY to new cis-elements
In angiosperms, flower development requires the combined action of the transcription factor
LEAFY (LFY) and the ubiquitin ligase adaptor F-box protein, UNUSUAL FLORAL ORGANS …
LEAFY (LFY) and the ubiquitin ligase adaptor F-box protein, UNUSUAL FLORAL ORGANS …
Strategies to maximize heterologous protein expression in Escherichia coli with minimal cost
Automation and miniaturization are key issues of high-throughput research projects in the
post-genomic era. The implementation of robotics and parallelization has enabled …
post-genomic era. The implementation of robotics and parallelization has enabled …
[HTML][HTML] Structural basis for oligomerization of auxin transcriptional regulators
MH Nanao, T Vinos-Poyo, G Brunoud… - Nature …, 2014 - nature.com
The plant hormone auxin is a key morphogenetic regulator acting from embryogenesis
onwards. Transcriptional events in response to auxin are mediated by the auxin response …
onwards. Transcriptional events in response to auxin are mediated by the auxin response …
A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity
Transcription factors (TFs) are key players in evolution. Changes affecting their function can
yield novel life forms but may also have deleterious effects. Consequently, gene duplication …
yield novel life forms but may also have deleterious effects. Consequently, gene duplication …