Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer

N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Phase-change contrast agents for imaging and therapy

PS Sheeran, PA Dayton - Current pharmaceutical design, 2012 - ingentaconnect.com
Phase-change contrast agents (PCCAs) for ultrasound-based applications have resulted in
novel ways of approaching diagnostic and therapeutic techniques beyond what is possible …

Magnetic cellulose nanocrystal stabilized Pickering emulsions for enhanced bioactive release and human colon cancer therapy

LE Low, LTH Tan, BH Goh, BT Tey, BH Ong… - International journal of …, 2019 - Elsevier
Stimuli-responsive drug release and controlled delivery play crucial roles in enhancing the
therapeutic efficacy and lowering over-dosage induced side effects. In this paper, we report …

Decafluorobutane as a phase-change contrast agent for low-energy extravascular ultrasonic imaging

PS Sheeran, VP Wong, S Luois, RJ McFarland… - Ultrasound in medicine …, 2011 - Elsevier
Currently available microbubbles used for ultrasound imaging and therapeutics are limited
to intravascular space due to their size distribution in the micron range. Phase-change …

Acoustic droplet vaporization is initiated by superharmonic focusing

O Shpak, M Verweij, HJ Vos… - Proceedings of the …, 2014 - National Acad Sciences
Acoustically sensitive emulsion droplets composed of a liquid perfluorocarbon have the
potential to be a highly efficient system for local drug delivery, embolotherapy, or for tumor …

[HTML][HTML] Current advances in ultrasound-combined nanobubbles for cancer-targeted therapy: a review of the current status and future perspectives

C Su, XJ Ren, F Nie, T Li, W Lv, H Li, Y Zhang - RSC advances, 2021 - pubs.rsc.org
The non-specific distribution, non-selectivity towards cancerous cells, and adverse off-target
side effects of anticancer drugs and other therapeutic molecules lead to their inferior clinical …

Aptamer-conjugated and drug-loaded acoustic droplets for ultrasound theranosis

CH Wang, ST Kang, YH Lee, YL Luo, YF Huang… - Biomaterials, 2012 - Elsevier
Tumor therapy requires multi-functional treatment strategies with specific targeting of
therapeutics to reduce general toxicity and increase efficacy. In this study we fabricated and …

[HTML][HTML] Stimuli-responsive hydrogels for local post-surgical drug delivery

E Askari, A Seyfoori, M Amereh, SS Gharaie… - Gels, 2020 - mdpi.com
Currently, surgical operations, followed by systemic drug delivery, are the prevailing
treatment modality for most diseases, including cancers and trauma-based injuries …

Nanoparticle‐loaded protein–polymer nanodroplets for improved stability and conversion efficiency in ultrasound imaging and drug delivery

J Lee, D Carugo, C Crake, J Owen… - Advanced …, 2015 - ora.ox.ac.uk
A new formulation of volatile nanodroplets stabilized by a protein and polymer coating and
loaded with magnetic nanoparticles is developed. The droplets show enhanced stability and …

[HTML][HTML] Ultrasound-responsive materials for drug/gene delivery

X Cai, Y Jiang, M Lin, J Zhang, H Guo, F Yang… - Frontiers in …, 2020 - frontiersin.org
Ultrasound is one of the most commonly used methods in the diagnosis and therapy of
diseases due to its safety, deep penetration into tissue, and non-invasive nature. In the …