Mass spectrometry approaches to monitor protein–drug interactions

N Zinn, C Hopf, G Drewes, M Bantscheff - Methods, 2012 - Elsevier
Recent advances in mass spectrometry-based approaches have enabled the investigation
of drug–protein interactions in various ways including the direct detection of drug–target …

Preparation of (−)-Nutlin-3 using enantioselective organocatalysis at decagram scale

TA Davis, AE Vilgelm, A Richmond… - The Journal of organic …, 2013 - ACS Publications
Chiral nonracemic cis-4, 5-bis (aryl) imidazolines have emerged as a powerful platform for
the development of cancer chemotherapeutics, stimulated by the Hoffmann-La Roche …

MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer

CM Croce, GA Calin - US Patent 8,658,370, 2014 - Google Patents
2009-03-30 Assigned to THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION
reassignment THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION ASSIGNMENT …

MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors

CM Croce, GA Calin - US Patent 8,389,210, 2013 - Google Patents
2010-09-20 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …

MicroRNA expression profiling and targeting in peripheral blood in lung cancer

SP Nana-Sinkam, CB Marsh, MG Piper… - US Patent App. 12 …, 2010 - Google Patents
US20100323357A1 - MicroRNA Expression Profiling and Targeting in Peripheral Blood in
Lung Cancer - Google Patents US20100323357A1 - MicroRNA Expression Profiling and …

Compositions and methods for the diagnosis and therapy of BCL2-associated cancers

CM Croce, GA Calin - US Patent 8,481,505, 2013 - Google Patents
The invention provides methods and compositions for the treatment of cancers associated
with overexpression of a BCL2 gene and/or gene productina Subject, and methods and …

MicroRNA Signatures in Human Ovarian Cancer

CM Croce - US Patent App. 12/676,670, 2010 - Google Patents
S&S 8888 Sssssssssss-six sass Sex: sis) is is says hSa-mir-200C 5.6 O2789 113584732
4.285621 5.1693. 7934 hSa-mir-141 6.66868 8.134845605 3.175124 4.632327322 hSa-mir …

Methods and compositions for inducing deregulation of EPHA7 and ERK phosphorylation in human acute leukemias

CM Croce - US Patent 8,466,119, 2013 - Google Patents
5,567,586 A 10, 1996 Croce 5,595,869 A 1/1997 Tsujimoto et al. 5,633,135 A 5, 1997
Croceet al.(57) ABSTRACT 5,633,136 A 5, 1997 Croceet al. Methods for assessing a …

Methods and compositions for the diagnosis and treatment of esphageal adenocarcinomas

CM Croce, CC Harris, EA Mathe - 2009 - Google Patents
This invention relates generally to the field of molecular biology. More particularly, it
concerns methods and compositions involving biomarkers for esophageal cancer and …

MiR-29-based methods for the diagnosis and prognosis of acute myeloid leukemia (AML)

CM Croce - US Patent 8,530,159, 2013 - Google Patents
US8530159B2 - MiR-29-based methods for the diagnosis and prognosis of acute myeloid
leukemia (AML) - Google Patents US8530159B2 - MiR-29-based methods for the diagnosis …