Integrative and mechanistic approach to the hair growth cycle and hair loss

N Natarelli, N Gahoonia, RK Sivamani - Journal of clinical medicine, 2023 - mdpi.com
The hair cycle is composed of four primary phases: anagen, catagen, telogen, and exogen.
Anagen is a highly mitotic phase characterized by the production of a hair shaft from the hair …

Alopecia areata: a review of the role of oxidative stress, possible biomarkers, and potential novel therapeutic approaches

L Peterle, S Sanfilippo, F Borgia, N Cicero, S Gangemi - Antioxidants, 2023 - mdpi.com
Alopecia areata (AA) is a dermatological condition characterized by non-scarring hair loss.
Exact etiopathogenesis of AA is still unknown although it is known that several factors …

Alopecia areata: review of epidemiology, clinical features, pathogenesis, and new treatment options

E Darwin, PA Hirt, R Fertig, B Doliner… - … journal of trichology, 2018 - journals.lww.com
Alopecia areata (AA) is a complex autoimmune condition that causes nonscarring hair loss.
It typically presents with sharply demarcated round patches of hair loss and may present at …

Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration

Q Zhao, Y Zheng, D Zhao, L Zhao, L Geng, S Ma… - Protein & …, 2023 - academic.oup.com
Hair loss affects millions of people at some time in their life, and safe and efficient treatments
for hair loss are a significant unmet medical need. We report that topical delivery of quercetin …

Design of a multifunctional biomaterial inspired by ancient Chinese medicine for hair regeneration in burned skin

Z Zhang, Q Dai, Y Zhang, H Zhuang… - … applied materials & …, 2020 - ACS Publications
In deep burn injuries, the dermis of the skin is often severely damaged, and hair follicles are
also lost and lose the potential for regeneration. Therefore, the development of wound …

Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3β/β-catenin signaling pathway

H Fu, W Li, Z Weng, Z Huang, J Liu, Q Mao… - Frontiers in …, 2023 - frontiersin.org
Cacumen Platycladi (CP) consists of the dried needles of Platycladus orientalis L.) Franco. It
was clinically demonstrated that it effectively regenerates hair, but the underlying …

Protective role of nutritional plants containing flavonoids in hair follicle disruption: A review

E Bassino, F Gasparri, L Munaron - International Journal of Molecular …, 2020 - mdpi.com
Hair loss is a disorder in which the hair falls out from skin areas such as the scalp and the
body. Several studies suggest the use of herbal medicine to treat related disorders …

Cytotoxic evaluation of Melia azedarach in comparison with, Azadirachta indica and its phytochemical investigation

S Jafari, S Saeidnia, H Hajimehdipoor… - DARU Journal of …, 2013 - Springer
Background Melia azedarach L. is an important medicinal plant that is used for variety of
ailments in Iranian traditional medicine. Azadirachta indica A. Juss is its allied species and …

Phospholipid–polymer hybrid nanoparticle-mediated transfollicular delivery of quercetin: prospective implement for the treatment of androgenic alopecia

L Das, M Kaurav, RS Pandey - Drug Development and Industrial …, 2019 - Taylor & Francis
Objectives: The aim of the study was to deliver effective doses of quercetin (Que) to the
lower region of hair follicles (HFs) using the transfollicular route through …

Innovative strategies for hair regrowth and skin visualization

Q Mai, Y Han, G Cheng, R Ma, Z Yan, X Chen, G Yu… - Pharmaceutics, 2023 - mdpi.com
Today, about 50% of men and 15–30% of women are estimated to face hair-related
problems, which create a significant psychological burden. Conventional treatments …