Introduction: Hematological disorders account for about 1.3% of all causes of acute stroke.
This systematized review presents updated information on the implications of this category …

All the adverse effects of heparins are related to their wide variety of biological activities, with
bleeding being the most important safety issue, resulting directly from the potency of heparin …

The article presents information on the diagnosis of the heparin-induced thrombocytopenia
(HIT). It informs about the diagnosis techniques used for HIT which includes enzyme-linked …

Therapeutic proteins provide innovative and effective therapies for numerous diseases.
However, some of these products are associated with unwanted immunogenicity that may …

The incidence of bleeding and thrombo-embolic complications in patients undergoing
mechanical circulatory support therapy remains high and is associated with bad outcomes …

Platelets are essential in maintaining hemostasis following inflammation or injury to the
vasculature. Dysregulated platelet activity often results in thrombotic complications leading …

This study was designed to investigate the incidence, causes, and outcomes of new-onset
thrombocytopenia (NOT) in Korean intensive care units (ICUs). A prospective cohort study …

Thromboembolism and bleeding after mechanical heart valve replacement are still unsolved
problems, particularly for patients requiring anticoagulative bridging therapy. The aim of this …

Generic forms of chemically-derived drugs must exhibit chemical identity and be
bioequivalent in healthy human subjects. The use of generic drugs results in a considerable …

Heparin-induced thrombocytopenia (HIT) is a thrombocytopenia caused by heparin and
mediated by an atypical immune mechanism leading to a paradoxical high thrombotic risk …