[HTML][HTML] Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism

J Gao, K Xu, H Liu, G Liu, M Bai, C Peng… - Frontiers in cellular and …, 2018 - frontiersin.org
The gut microbiota influences the health of the host, especially with regard to gut immune
homeostasis and the intestinal immune response. In addition to serving as a nutrient …

Gut biogeography of the bacterial microbiota

GP Donaldson, SM Lee, SK Mazmanian - Nature Reviews Microbiology, 2016 - nature.com
Animals assemble and maintain a diverse but host-specific gut microbial community. In
addition to characteristic microbial compositions along the longitudinal axis of the intestines …

[HTML][HTML] Regional diversity of the gastrointestinal microbiome

K Martinez-Guryn, V Leone, EB Chang - Cell host & microbe, 2019 - cell.com
The role of gut microbes in health and disease has often been surmised from stool, which is
easily sampled and rich in microbial diversity, density, and abundance. Microbial analyses …

Kynurenine pathway metabolism and the microbiota-gut-brain axis

PJ Kennedy, JF Cryan, TG Dinan, G Clarke - Neuropharmacology, 2017 - Elsevier
It has become increasingly clear that the gut microbiota influences not only gastrointestinal
physiology but also central nervous system (CNS) function by modulating signalling …

Regional specialization within the intestinal immune system

AM Mowat, WW Agace - Nature Reviews Immunology, 2014 - nature.com
The intestine represents the largest compartment of the immune system. It is continually
exposed to antigens and immunomodulatory agents from the diet and the commensal …

Minireview: gut microbiota: the neglected endocrine organ

G Clarke, RM Stilling, PJ Kennedy… - Molecular …, 2014 - academic.oup.com
The concept that the gut microbiota serves as a virtual endocrine organ arises from a
number of important observations. Evidence for a direct role arises from its metabolic …

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10−/− mice

S Devkota, Y Wang, MW Musch, V Leone… - Nature, 2012 - nature.com
The composite human microbiome of Western populations has probably changed over the
past century, brought on by new environmental triggers that often have a negative impact on …

[HTML][HTML] Intestinal microbiota in human health and disease: the impact of probiotics

J Gerritsen, H Smidt, GT Rijkers, WM de Vos - Genes & nutrition, 2011 - Springer
The complex communities of microorganisms that colonise the human gastrointestinal tract
play an important role in human health. The development of culture-independent molecular …

[HTML][HTML] Nutrients mediate intestinal bacteria–mucosal immune crosstalk

N Ma, P Guo, J Zhang, T He, SW Kim… - Frontiers in …, 2018 - frontiersin.org
The intestine is the shared site of nutrient digestion, microbiota colonization and immune cell
location and this geographic proximity contributes to a large extent to their interaction. The …

[HTML][HTML] Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice

F Hildebrand, TLA Nguyen, B Brinkman, RG Yunta… - Genome biology, 2013 - Springer
Background Murine models are a crucial component of gut microbiome research.
Unfortunately, a multitude of genetic backgrounds and experimental setups, together with …