A substantial loss of muscle mass and strength (sarcopenia), a decreased regenerative
capacity, and a compromised physical performance are hallmarks of aging skeletal muscle …

Congenital myasthenic syndromes (CMS) are a heterogeneous group of disorders
characterized by impaired neuromuscular signal transmission due to germline pathogenic …

The COVID-19 pandemic is an unprecedented health crisis as entire populations have been
asked to self-isolate and live in home-confinement for several weeks to months, which in …

Exercise stimulates the release of proteins with autocrine, paracrine, or endocrine functions
produced in skeletal muscle, termed myokines. Based on the current state of knowledge, the …

Aging is associated with a progressive loss of muscle mass and strength and a decline in
neurophysiological functions. Age-related neuromuscular junction (NMJ) plays a key role in …

Increasing evidence indicates that exercise has beneficial effects on chronic inflammation,
cardiorespiratory function, muscle and bone strength and metabolic markers in adults with …

Key points Few days of unloading are sufficient to induce a decline of skeletal muscle mass
and function; notably, contractile force is lost at a faster rate than muscle mass. The reasons …

Declines in physical performance and cognition are commonly observed in older adults. The
geroscience paradigm posits that a set of processes and pathways shared among age …

Background The assessment of muscle mass is a key determinant of the diagnosis of
sarcopenia. We introduce for the first time an ultrasound imaging method for diagnosing …

Ageing is accompanied by an inexorable loss of muscle mass and functionality and
represents a major risk factor for numerous diseases such as cancer, diabetes and …