Platelet-rich plasma: new performance understandings and therapeutic considerations in 2020

P Everts, K Onishi, P Jayaram, JF Lana… - International journal of …, 2020 - mdpi.com
Emerging autologous cellular therapies that utilize platelet-rich plasma (PRP) applications
have the potential to play adjunctive roles in a variety of regenerative medicine treatment …

The role of vitamin C, vitamin D, and selenium in immune system against COVID-19

M Bae, H Kim - Molecules, 2020 - mdpi.com
Low levels of micronutrients have been associated with adverse clinical outcomes during
viral infections. Therefore, to maximize the nutritional defense against infections, a daily …

Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action

C Pifferi, R Fuentes, A Fernández-Tejada - Nature Reviews Chemistry, 2021 - nature.com
Modern subunit vaccines based on homogeneous antigens offer more precise targeting and
improved safety compared with traditional whole-pathogen vaccines. However, they are also …

Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation

V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …

Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis

SJ Gaudino, P Kumar - Frontiers in immunology, 2019 - frontiersin.org
Innate immunity is maintained in part by antigen presenting cells (APCs) including dendritic
cells, macrophages, and B cells. APCs interact with T cells to link innate and adaptive …

T-helper cell subset response is a determining factor in COVID-19 progression

FJ Gil-Etayo, P Suàrez-Fernández… - Frontiers in cellular …, 2021 - frontiersin.org
The immune response type organized against viral infection is determinant in the prognosis
of some infections. This work has aimed to study Th polarization in acute COVID-19 and its …

[HTML][HTML] The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators

HM Habib, S Ibrahim, A Zaim, WH Ibrahim - Biomedicine & …, 2021 - Elsevier
Iron overload is increasingly implicated as a contributor to the pathogenesis of COVID-19.
Indeed, several of the manifestations of COVID-19, such as inflammation, hypercoagulation …

The JNK signaling pathway in inflammatory skin disorders and cancer

MB Hammouda, AE Ford, Y Liu, JY Zhang - Cells, 2020 - mdpi.com
The c-Jun N-terminal kinases (JNKs), with its members JNK1, JNK2, and JNK3, is a
subfamily of (MAPK) mitogen-activated protein kinases. JNK signaling regulates a wide …

Gut microbiota regulation of T cells during inflammation and autoimmunity

EM Brown, DJ Kenny, RJ Xavier - Annual review of immunology, 2019 - annualreviews.org
The intestinal microbiota plays a crucial role in influencing the development of host
immunity, and in turn the immune system also acts to regulate the microbiota through …

Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2022 - Elsevier
Abstract oxidative stress is caused by an abundant generation of reactive oxygen species,
associated to a diminished capacity of the endogenous systems of the organism to …