Nonenzymatic nitric oxide (NO) generation via the reduction of nitrate and nitrite ions, along
with remarkably high levels of nitrate ions in skeletal muscle, have been described recently …

Defects in neuronal nitric oxide synthase (nNOS) splice variant localization and signaling in
skeletal muscle are a firmly established pathogenic characteristic of many neuromuscular …

Key points Nitric oxide (NO), a potent vasodilator and a regulator of many physiological
processes, is produced in mammals both enzymatically and by reduction of nitrite and nitrate …

Objective: To conduct a randomized trial to test the primary hypothesis that once-daily
tadalafil, administered orally for 48 weeks, lessens the decline in ambulatory ability in boys …

Oral consumption of inorganic nitrate, which is abundant in green leafy vegetables and
roots, has been shown to increase circulating plasma nitrite concentration, which can be …

Duchenne muscular dystrophy (DMD) is a devastating chromosome X-linked disease that
manifests predominantly in progressive skeletal muscle wasting and dysfunctions in the …

Nitric oxide (NO)(co) regulates many physiological processes in the body. Its short-lived free
radicals force synthesis in situ and on-demand, without storage possibility. Local oxygen …

Neuronal nitric oxide synthase (nNOS) is involved in nitric oxide (NO) production and
suggested to play a crucial role in blood flow regulation of skeletal muscle. During activation …

In recent years, complementary and alternative medicine has become increasingly popular.
This trend has not escaped the Duchenne Muscular Dystrophy community with one study …

Duchenne muscular dystrophy arises from the loss of dystrophin and is characterized by
calcium dysregulation, muscular atrophy, and metabolic dysfunction. The secondary …