Advancing therapeutics for recurrent clostridioides difficile infections: an overview of vowst's FDA approval and implications
Clostridioides difficile infections (CDI) are a leading cause of healthcare-associated
infections with a high relapse rate. Current treatment guidelines recommend fidaxomicin as …
infections with a high relapse rate. Current treatment guidelines recommend fidaxomicin as …
Microbiome-Related and Infection Control Approaches to Primary and Secondary Prevention of Clostridioides difficile Infections
LV McFarland, EJC Goldstein, R Kullar - Microorganisms, 2023 - mdpi.com
Clostridioides difficile infections (CDIs) have decreased in the past years, but since 2021,
some hospitals have reported an increase in CDI rates. CDI remains a global concern and …
some hospitals have reported an increase in CDI rates. CDI remains a global concern and …
Microbiota-Based Live Biotherapeutic Products for Clostridioides Difficile Infection- The Devil is in the Details
L Monday, G Tillotson, T Chopra - Infection and Drug Resistance, 2024 - Taylor & Francis
Clostridioides difficile infection (CDI) remains a significant contributor to healthcare costs
and morbidity due to high rates of recurrence. Currently, available antibiotic treatment …
and morbidity due to high rates of recurrence. Currently, available antibiotic treatment …
RBX2660 (REBYOTA®) in preventing recurrence of Clostridioides difficile infection: a profile of its use in the USA
HA Blair - Drugs & Therapy Perspectives, 2023 - Springer
Abstract RBX2660 (fecal microbiota, live-jslm; REBYOTA®) is an emerging option for the
prevention of recurrent Clostridioides difficile infection (CDI) following standard of care …
prevention of recurrent Clostridioides difficile infection (CDI) following standard of care …
PhosphoLipidome Alteration Induced by Clostridioides difficile Toxin B in Enteric Glial Cells
Clostridioides difficile (C. difficile) is responsible for a spectrum of nosocomial/antibiotic-
associated gastrointestinal diseases that are increasing in global incidence and mortality …
associated gastrointestinal diseases that are increasing in global incidence and mortality …
Alternative treatment of recurrent Clostridioides difficile infection in adults by fecal transplantation: an overview of phase I–IV studies from Clinicaltrials.gov
NA Obaid - Frontiers in Microbiology, 2024 - frontiersin.org
Background Fecal microbiota transplantation (FMT) is an interventional approach to treat
chronic and recurrent Clostridioides difficile infection (CDI). However, there is insufficient …
chronic and recurrent Clostridioides difficile infection (CDI). However, there is insufficient …
In-vitro determination of inhibitory effects of probiotic strains on Clostridioides difficile
Commercial probiotic strains inhibited C. difficile, and other Clostridium cultures with zones
14.2–78.9 mm. The highest inhibition was observed with commercial culture on C. difficile …
14.2–78.9 mm. The highest inhibition was observed with commercial culture on C. difficile …
The conundrum of bacteria-specific antibiotics
S Datta - Journal of Antimicrobial Chemotherapy, 2023 - academic.oup.com
There is a continual debate on the pros and cons of broad-spectrum versus pathogen-
specific antibiotics. The unmet need for a solution for antimicrobial resistance (AMR) has put …
specific antibiotics. The unmet need for a solution for antimicrobial resistance (AMR) has put …
Modulating gut microbiota for treating antibiotic-associated diarrhea from Clostridium difficile infection: insights from Lizhong decoction and its polysaccharide …
XQ Rong, QL Shu - Letters in Applied Microbiology, 2024 - academic.oup.com
To investigate whether the polysaccharide component of the Traditional Chinese Medicine
(TCM) formula Lizhong decoction (LZD) has therapeutic effects and regulates gut microbiota …
(TCM) formula Lizhong decoction (LZD) has therapeutic effects and regulates gut microbiota …
[HTML][HTML] Therapeutics involved in managing initial and recurrent Clostridium difficile infection: An updated literature review
VK Nagesh, HHV Tran, D Elias… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Clostridium difficile infection (CDI) has been increasing due to the effect of recurrent
hospitalizations. The use of antibiotics has been shown to alter the gut microbiome and lead …
hospitalizations. The use of antibiotics has been shown to alter the gut microbiome and lead …