Fracture risk is increased in patients with type 2 diabetes mellitus (T2DM). In addition, these
patients sustain fractures despite having higher levels of areal bone mineral density, as …

Improvements in health care and lifestyle have led to an elevated lifespan and increased
focus on age-associated diseases, such as neurodegeneration, cardiovascular disease …

Diabetes mellitus is a metabolic disorder that increases fracture risk, interferes with bone
formation, and impairs fracture healing. Type 1 diabetes mellitus (T1DM) and type 2 …

Diabetes compromises bone cell metabolism and function, resulting in increased risk of
fragility fracture. Advanced glycation end products (AGEs) interact with the receptor for AGEs …

Diabetes mellitus (a group of metabolic disorders characterized by hyperglycemia) and
periodontitis (a microbially induced inflammatory disorder that affects the supporting …

Aims To review the evidence for the molecular and cellular processes that may potentially
link periodontal disease and diabetes. The pathogenic roles of cytokines and metabolic …

The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …

Diabetes mellitus and periodontal disease are chronic diseases affecting a large number of
populations worldwide. Changed bone metabolism is one of the important long-term …

Collagen cross-linking, a major post-translational modification of collagen, plays important
roles in the biological and biomechanical features of bone. Collagen cross-links can be …

The present narrative review examines the scientific evidence of the biological mechanisms
that may link periodontitis and diabetes, as a source of comorbidity. Publications regarding …