From synapses to circuits, astrocytes regulate behavior
Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior.
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …
Chemogenetic modulation of astrocytes and microglia: State‐of‐the‐art and implications in neuroscience
J Bossuyt, Y Van Den Herrewegen, L Nestor, A Buckinx… - Glia, 2023 - Wiley Online Library
Insights into the role astrocytes and microglia play in normal and diseased brain functioning
has expanded drastically over the last decade. Recently, chemogenetic tools have emerged …
has expanded drastically over the last decade. Recently, chemogenetic tools have emerged …
Side-by-side comparison of the effects of Gq-and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the …
Y Van Den Herrewegen, TM Sanderson, S Sahu… - Molecular Brain, 2021 - Springer
Astrocytes express a plethora of G protein-coupled receptors (GPCRs) that are crucial for
shaping synaptic activity. Upon GPCR activation, astrocytes can respond with transient …
shaping synaptic activity. Upon GPCR activation, astrocytes can respond with transient …
Astrocyte structural heterogeneity in the mouse hippocampus
JF Viana, JL Machado, DS Abreu, A Veiga, S Barsanti… - Glia, 2023 - Wiley Online Library
Astrocytes are integral components of brain circuits, where they sense, process, and
respond to surrounding activity, maintaining homeostasis and regulating synaptic …
respond to surrounding activity, maintaining homeostasis and regulating synaptic …
Astrocyte and L-lactate in the anterior cingulate cortex modulate schema memory and neuronal mitochondrial biogenesis
Astrocyte-derived L-lactate was shown to confer beneficial effects on synaptic plasticity and
cognitive functions. However, how astrocytic G i signaling in the anterior cingulate cortex …
cognitive functions. However, how astrocytic G i signaling in the anterior cingulate cortex …
Know thy SEFL: Fear sensitization and its relevance to stressor-related disorders
Extreme stress can cause long-lasting changes in affective behavior manifesting in
conditions such as post-traumatic stress disorder (PTSD). Understanding the biological …
conditions such as post-traumatic stress disorder (PTSD). Understanding the biological …
Role of hydrogen sulfide and polysulfides in neurological diseases: focus on protein S-persulfidation
Hydrogen sulfide (H2S) and hydrogen polysulfides are recognized as important signaling
molecules that are generated physiologically in the body, including the central nervous …
molecules that are generated physiologically in the body, including the central nervous …
Stress‐induced structural and functional modifications of astrocytes—Further implicating glia in the central response to stress
An organism's response to stress requires activation of multiple brain regions. This can have
long‐lasting effects on synaptic transmission and plasticity that likely provide adaptive …
long‐lasting effects on synaptic transmission and plasticity that likely provide adaptive …
[HTML][HTML] Astrocytes control recent and remote memory strength by affecting the recruitment of the CA1→ ACC projection to engrams
The maturation of engrams from recent to remote time points involves the recruitment of CA1
neurons projecting to the anterior cingulate cortex (CA1→ ACC). Modifications of G-protein …
neurons projecting to the anterior cingulate cortex (CA1→ ACC). Modifications of G-protein …
Macro-and microscale stress–associated alterations in brain structure: Translational link with depression
Major depressive disorder (MDD) is a stress-related disorder associated with many
cytoarchitectural and neurochemical changes. However, the majority of these changes …
cytoarchitectural and neurochemical changes. However, the majority of these changes …