Nanotechnology‐driven strategies to enhance the treatment of drug‐resistant bacterial infections

J Zhang, M Liu, H Guo, S Gao, Y Hu… - Wiley …, 2024 - Wiley Online Library
The misuse of antibiotics has led to increased bacterial resistance, posing a global public
health crisis and seriously endangering lives. Currently, antibiotic therapy remains the most …

Spectroscopic Identification of Bacteria Resistance to Antibiotics by Means of Absorption of Specific Biochemical Groups and Special Machine Learning Algorithm

CP Barrera-Patiño, JM Soares, KC Branco, NM Inada… - Antibiotics, 2023 - mdpi.com
FTIR (Fourier transform infrared spectroscopy) is one analytical technique of the absorption
of infrared radiation. FTIR can also be used as a tool to characterize profiles of biomolecules …

Photodynamic inactivation of bacteria: Why it is not enough to excite a photosensitizer

GA Meerovich, EV Akhlyustina, ID Romanishkin… - Photodiagnosis and …, 2023 - Elsevier
Background The development of multidrug resistance (MDR) in infectious agents is one of
the most serious global problems facing humanity. Antimicrobial photodynamic therapy …

α-ketoglutarate downregulates thiosulfate metabolism to enhance antibiotic killing

L Peng, S Tian, W Guo, X Chen, J Wu, Y Liu… - International Journal of …, 2024 - Elsevier
Potentiation of the effects of currently available antibiotics is urgently required to tackle the
rising antibiotics resistance. The pyruvate (P) cycle has been shown to play a critical role in …

[HTML][HTML] Photodynamic activation of phytochemical-antibiotic combinations for combatting Staphylococcus aureus from acute wound infections

ASC Gonçalves, MM Leitão, JR Fernandes… - … of Photochemistry and …, 2024 - Elsevier
Staphylococcus aureus is characterized by its high resistance to conventional antibiotics,
particularly methicillin-resistant (MRSA) strains, making it a predominant pathogen in acute …

[HTML][HTML] Strategies for overcoming the lung surfactant barrier and achieving success in antimicrobial photodynamic therapy

IA de Lima, LG Fiuza, JSD Tovar, DSL Bejar… - … of Photochemistry and …, 2024 - Elsevier
The impressive increase in antimicrobial resistance has required the development of
alternative treatments that act on multiple non-specific molecular targets and are effective …

Photodynamic inactivation of E. coli with cationic imidazolyl-porphyrin photosensitizers and their synergic combination with antimicrobial cinnamaldehyde

MFC Silva, RT Aroso, JM Dabrowski, B Pucelik… - Photochemical & …, 2024 - Springer
Bacterial infections are a global health concern, particularly due to the increasing resistance
of bacteria to antibiotics. Multi-drug resistance (MDR) is a considerable challenge, and novel …

[HTML][HTML] Machine Learning in FTIR Spectrum for the Identification of Antibiotic Resistance: A Demonstration with Different Species of Microorganisms

CP Barrera Patiño, JM Soares, KC Blanco, VS Bagnato - Antibiotics, 2024 - mdpi.com
Recent studies introduced the importance of using machine learning algorithms in research
focused on the identification of antibiotic resistance. In this study, we highlight the …

[HTML][HTML] Guided Plasma Application in Dentistry—An Alternative to Antibiotic Therapy

T Gross, LA Ledernez, L Birrer, ME Bergmann… - …, 2024 - pmc.ncbi.nlm.nih.gov
Cold atmospheric plasma (CAP) is a promising alternative to antibiotics and chemical
substances in dentistry that can reduce the risk of unwanted side effects and bacterial …

Оn the aggregation of polycationic photosensitizer upon binding to Gram-negative bacteria

ID Romanishkin, EV Akhlyustina… - … and Applications in …, 2024 - iopscience.iop.org
Polycationic photosensitizers (PS) are not susceptible to aggregation in solutions, but their
high local concentrations in Gram-negative bacteria can be sufficient for aggregation and …