African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Human African Trypanosomiasis (HAT, sleeping sickness) and Animal African
Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same …

African trypanosomes are vector-borne protozoa, which cause significant human and animal
disease across sub-Saharan Africa, and animal disease across Asia and South America. In …

Emerging infectious diseases continue to pose a significant burden on global public health,
and there is a critical need to better understand transmission dynamics arising at the …

Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …

Background Trypanosoma brucei brucei evades host immune responses by multiple means,
including the disruption of B-cell homeostasis. This hampers anti-trypanosome vaccine …

Human parasitic infections—including malaria, and many neglected tropical diseases
(NTDs)—have long represented a Gordian knot in global public health: ancient, persistent …

Laboratory studies of pathogens aim to limit complexity in order to disentangle the important
parameters contributing to an infection. However, pathogens rarely exist in isolation, and …

Trypanosomiases are a group of tropical diseases that have devastating health and socio-
economic effects worldwide. In humans, these diseases are caused by the pathogenic …

Animal trypanosomiasis (AT) is a parasitic disease with high socio-economic impact. Given
the limited therapeutic options and problems of toxicity and drug resistance, this study …