Allogeneic vs. autologous mesenchymal stem/stromal cells in their medication practice

C Li, H Zhao, L Cheng, B Wang - Cell & Bioscience, 2021 - Springer
Mesenchymal stem/stromal cell (MSC)-based therapeutics is already available for treatment
of a range of diseases or medical conditions. Autologous or allogeneic MSCs obtained from …

The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy

J Zhang, X Huang, H Wang, X Liu, T Zhang… - Stem cell research & …, 2015 - Springer
Mesenchymal stem cells (MSCs) are ideal for cell-based therapy in various inflammatory
diseases because of their immunosuppressive and tissue repair properties. Moreover, their …

[HTML][HTML] Mesenchymal stem cells: Immunomodulatory capability and clinical potential in immune diseases

Q Zhao, H Ren, Z Han - Journal of cellular immunotherapy, 2016 - Elsevier
Mesenchymal stem cells (MSCs) represent a heterogenous population of adult, fibroblast-
like multi-potent cells. MSCs have drawn much attention during the last decade in the field of …

Immunoprivileged no more: measuring the immunogenicity of allogeneic adult mesenchymal stem cells

AK Berglund, LA Fortier, DF Antczak… - Stem cell research & …, 2017 - Springer
Background Autologous and allogeneic adult mesenchymal stem/stromal cells (MSCs) are
increasingly being investigated for treating a wide range of clinical diseases. Allogeneic …

Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study

J Liang, H Zhang, B Hua, H Wang, L Lu, S Shi… - Annals of the …, 2010 - ard.bmj.com
Objective To determine the safety and efficacy of allogeneic mesenchymal stem cell
transplantation (MSCT) in refractory systemic lupus erythematosus (SLE). Methods A total of …

Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience

D Wang, H Zhang, J Liang, X Li, X Feng… - Cell …, 2013 - journals.sagepub.com
Mesenchymal stem cells (MSCs) are multipotential nonhematopoietic progenitors and are
capable of differentiating into several tissues of mesenchymal origin. We have shown that …

Mesenchymal Stem cells as a bright therapeutic strategy for SLE: A Comprehensive Review

HR Youshanlouei, H Valizadeh, A Tahavvori… - …, 2023 - search.proquest.com
Systemic lupus erythematosus (SLE) is a heterogeneous, chronic autoimmune disorder that
influences different systems. The pathogenesis of the SLE accompanies various T …

Mesenchymal stem cells in homeostasis and systemic diseases: hypothesis, evidences, and therapeutic opportunities

FJ Vizoso, N Eiro, L Costa, P Esparza… - International journal of …, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are present in all organs and tissues, playing a well-known
function in tissue regeneration. However, there is also evidence indicating a broader role of …

Adipose-derived mesenchymal stem cells in autoimmune disorders: state of the art and perspectives for systemic sclerosis

ATJ Maria, M Maumus, A Le Quellec… - Clinical reviews in …, 2017 - Springer
Mesenchymal stromal/stem cells (MSC) are non-hematopoietic multipotent progenitor cells,
first described in bone marrow in the middle of last century. Since then, MSC have been the …

Mesenchymal stem cells: allogeneic MSC may be immunosuppressive but autologous MSC are dysfunctional in lupus patients

RJ Cheng, AJ Xiong, YH Li, SY Pan… - Frontiers in cell and …, 2019 - frontiersin.org
Mesenchymal stem cells (MSCs) have a potently immunosuppressive capacity in both
innate and adaptive immune responses. Consequently, MSCs transplantation has emerged …