The predominantly anaerobic microbiota of the distal ileum and colon contain an
extraordinarily complex variety of metabolically active bacteria and fungi that intimately …

OBJECTIVES: To review the frequency with which infliximab loses its effect and dose
“intensification” is required for Crohn's disease treatment. METHODS: Bibliographical …

Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

OBJECTIVE. The objective of our study was to prospectively obtain pilot data on the
accuracy of MR enterography for detecting small-bowel Crohn's disease compared with CT …

Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the
gastrointestinal tract. While a cure remains elusive, both can be treated with medications that …

Tumor necrosis factor-α (TNFα) is a key proinflammatory cytokine involved in chronic
inflammatory diseases. Infliximab, a chimeric (human-murine) monoclonal IgG1 anti-TNFα …

Background Differential immunoregulatory capabilities of probiotic Lactobacillus were
explored in the context of pediatric Crohn's disease. Experimental strategies addressed …

Women with inflammatory bowel disease (IBD) have similar rates of fertility to the general
population, but have an increased rate of adverse pregnancy outcomes compared with the …

Standard of care for ulcerative colitis involves long‐term pharmacotherapy or colectomy.
Approximately 20% to 30% of patients eventually require a colectomy because patients …

Crohn's disease and ulcerative colitis, collectively known as the inflammatory bowel
diseases (IBD), are largely diseases of the twentieth century, and are associated with the …