Iron overload in human disease
RE Fleming, P Ponka - New England Journal of Medicine, 2012 - Mass Medical Soc
Iron Overload in Human Disease | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Non-transferrin bound iron: a key role in iron overload and iron toxicity
P Brissot, M Ropert, C Le Lan, O Loréal - Biochimica et Biophysica Acta …, 2012 - Elsevier
BACKGROUND: Besides transferrin iron, which represents the normal form of circulating
iron, non-transferrin bound iron (NTBI) has been identified in the plasma of patients with …
iron, non-transferrin bound iron (NTBI) has been identified in the plasma of patients with …
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …
DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …
death, often characterised by circumstances in which cells or tissues do not merely die and …
Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 …
Q Zheng, Y Zhao, J Guo, S Zhao, C Fei, C Xiao… - Cell death & …, 2018 - nature.com
Iron overload (IO) has been reported to contribute to mesenchymal stromal cell (MSC)
damage, but the precise mechanism has yet to be clearly elucidated. In this study, we found …
damage, but the precise mechanism has yet to be clearly elucidated. In this study, we found …
Non transferrin bound iron: nature, manifestations and analytical approaches for estimation
M Patel, D Ramavataram - Indian journal of clinical biochemistry, 2012 - Springer
Iron is an essential trace element and plays a number of vital roles in biological system. It
also leads the chains of pathological actions if present in excess and/or present in free form …
also leads the chains of pathological actions if present in excess and/or present in free form …
Complex confounder-corrected R2* mapping for liver iron quantification with MRI
D Hernando, RJ Cook, N Qazi, CA Longhurst… - European …, 2021 - Springer
Objectives MRI-based R2* mapping may enable reliable and rapid quantification of liver iron
concentration (LIC). However, the performance and reproducibility of R2* across acquisition …
concentration (LIC). However, the performance and reproducibility of R2* across acquisition …
Iron overload in sickle cell disease
R Raghupathy, D Manwani, JA Little - Advances in hematology, 2010 - Wiley Online Library
In sickle cell disease transfusions improve blood flow by reducing the proportion of red cells
capable of forming sickle hemoglobin polymer. This limits hemolysis and the endothelial …
capable of forming sickle hemoglobin polymer. This limits hemolysis and the endothelial …
Quercetin as a shuttle for labile iron
MM Baccan, O Chiarelli-Neto, RMS Pereira… - Journal of inorganic …, 2012 - Elsevier
The antioxidant activity of flavonoids may involve their ability to complex body iron in non-
redox-active forms. In this study, it was found that the catechol flavonoids rutin and quercetin …
redox-active forms. In this study, it was found that the catechol flavonoids rutin and quercetin …
Iron chelation therapy in myelodysplastic syndromes: where do we stand?
Anemia leading to transfusion dependency (TD) and iron overload (IO) is commonly
observed in patients with myelodysplastic syndromes (MDS). In MDS, TD and IO have been …
observed in patients with myelodysplastic syndromes (MDS). In MDS, TD and IO have been …
Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox
S Kikuchi, M Kobune, S Iyama, T Sato, K Murase… - Free Radical Biology …, 2012 - Elsevier
Myelodysplastic syndrome (MDS) is characterized by dysplastic and ineffective
hematopoiesis, peripheral blood cytopenias, and a risk of leukemic transformation. Most …
hematopoiesis, peripheral blood cytopenias, and a risk of leukemic transformation. Most …