The Genetic Variability of APOE in Different Human Populations and Its Implications for Longevity

P Abondio, M Sazzini, P Garagnani, A Boattini, D Monti… - Genes, 2019 - mdpi.com
Human longevity is a complex phenotype resulting from the combinations of context-
dependent gene-environment interactions that require analysis as a dynamic process in a …

Restoration of dysbiotic human gut microbiome for homeostasis

K Dixit, D Chaudhari, D Dhotre, Y Shouche, S Saroj - Life sciences, 2021 - Elsevier
The human microbiome is a complex and dynamic ecosystem, and the imbalance of its
microbial community structure from the normal state is termed dysbiosis. The dysbiotic gut …

Sulfated polysaccharides from Undaria pinnatifida improved high fat diet-induced metabolic syndrome, gut microbiota dysbiosis and inflammation in BALB/c mice

P Jiang, W Zheng, X Sun, G Jiang, S Wu, Y Xu… - International journal of …, 2021 - Elsevier
Undaria pinnatifida was shown to reduce serum lipids and fat accumulation and produce
beneficial effect on type 2 diabetes, but its effect on intestinal micro-ecology remains …

Bifidobacterium breve and Bifidobacterium longum Attenuate Choline-Induced Plasma Trimethylamine N-Oxide Production by Modulating Gut Microbiota in Mice

Q Wang, M Guo, Y Liu, M Xu, L Shi, X Li, J Zhao… - Nutrients, 2022 - mdpi.com
Atherosclerosis is the main cause of myocardial infarction and stroke, and the morbidity and
mortality rates of cardiovascular disease are among the highest of any disease worldwide …

Intermittent fasting positively modulates human gut microbial diversity and ameliorates blood lipid profile

MN Khan, SI Khan, MI Rana, A Ayyaz… - Frontiers in …, 2022 - frontiersin.org
Aim The aim was to evaluate the impact of intermittent fasting (IF) on human body mass
index (BMI) and serum lipid profile thorough constructive rectification of gut microbiota …

Endurance exercise ameliorates Western diet–induced atherosclerosis through modulation of microbiota and its metabolites

WC Huang, CL Tung, YCSH Yang, IH Lin, XE Ng… - Scientific reports, 2022 - nature.com
Abstract The World Health Organization determined cardiovascular disease to be the
leading cause of death globally; atherosclerosis is the primary cause of the high morbidity …

Sugars and gastrointestinal health

D Arnone, C Chabot, AC Heba, T Kökten… - Clinical …, 2022 - Elsevier
Sugar overconsumption is linked to a rise in the incidence of noncommunicable diseases
such as diabetes, cardiovascular diseases, and cancer. This increased incidence is …

Short-term western diet intake promotes IL-23‒mediated skin and joint inflammation accompanied by changes to the gut microbiota in mice

Z Shi, X Wu, CS Rocha, M Rolston… - Journal of Investigative …, 2021 - Elsevier
We previously showed that exposure to a high-sugar and moderate-fat diet (ie, Western diet
[WD]) in mice induces appreciable skin inflammation and enhances the susceptibility to …

Mannan oligosaccharide suppresses lipid accumulation and appetite in western‐diet‐induced obese mice via reshaping gut microbiome and enhancing short‐chain …

S Yan, R Shi, L Li, S Ma, H Zhang, J Ye… - Molecular nutrition & …, 2019 - Wiley Online Library
Scope Obesity is associated with gut microbiome dysbiosis. Mannose oligosaccharide
(MOS) has been reported to be a potential prebiotic. The present study is aimed to …

Intermittent hypoxia and hypercapnia alter diurnal rhythms of luminal gut microbiome and metabolome

C Allaband, A Lingaraju, C Martino, B Russell… - Msystems, 2021 - Am Soc Microbiol
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia and hypercapnia
(IHC), affects the composition of the gut microbiome and metabolome. The gut microbiome …