Shigella is the leading cause of global diarrheal deaths that currently lacks a licensed
vaccine. Shigellosis drives antimicrobial resistance and leads to economic impact through …

Type III secretion systems (T3SSs) are complex bacterial structures that provide gram-
negative pathogens with a unique virulence mechanism enabling them to inject bacterial …

Shigellosis is a global human health problem. Four species of Shigella ie S. dysenteriae, S.
flexneri, S. boydii and S. sonnei are able to cause the disease. These species are …

Background The burden of shigellosis is greatest in resource-poor countries. Although this
diarrheal disease has been thought to cause considerable morbidity and mortality in excess …

More than 50 years of research has yielded numerous Shigella vaccine candidates that
have exemplified both the promise of vaccine-induced prevention of shigellosis and the …

Shigella flexneri is a gram-negative bacterium which causes the most communicable of
bacterial dysenteries, shigellosis. Shigellosis causes 1.1 million deaths and over 164 million …

We determined the complete genome sequence of Shigella flexneri serotype 2a strain
2457T (4,599,354 bp). Shigella species cause> 1 million deaths per year from dysentery …

Background. Noroviruses cause significant morbidity and mortality from acute gastroenteritis
in all age groups worldwide. Methods. We conducted 2 phase 1 double-blind, controlled …

Shigellosis is one of the major causes of diarrhoea in India. The accurate estimates of
morbidity and mortality due to shigellosis are lacking, though it is endemic in the country and …

Worldwide, enteric infections rank third among all causes of disease burden, being
responsible for some 1.7–2.5 million deaths per year, mostly in young children and infants in …