Metabolomic strategies in biomarker research–new approach for indirect identification of drug consumption and sample manipulation in clinical and forensic …
AE Steuer, L Brockbals, T Kraemer - Frontiers in Chemistry, 2019 - frontiersin.org
Drug of abuse (DOA) consumption is a growing problem worldwide, particularly with
increasing numbers of new psychoactive substances (NPS) entering the drug market …
increasing numbers of new psychoactive substances (NPS) entering the drug market …
Metabolism and metabolomics of opiates: A long way of forensic implications to unravel
RJ Dinis-Oliveira - Journal of Forensic and Legal Medicine, 2019 - Elsevier
Opium poppy has important medical, socioeconomic, forensic and political implications.
More than 80 benzylisoquinoline alkaloids have been described, many of them with relevant …
More than 80 benzylisoquinoline alkaloids have been described, many of them with relevant …
Comparative metabolism of tramadol and tapentadol: a toxicological perspective
Tramadol and tapentadol are centrally acting, synthetic opioid analgesics used in the
treatment of moderate to severe pain. Main metabolic patterns for these drugs in humans are …
treatment of moderate to severe pain. Main metabolic patterns for these drugs in humans are …
¹H NMR-based metabolic profiling of human rectal cancer tissue
H Wang, L Wang, H Zhang, P Deng, J Chen, B Zhou… - Molecular cancer, 2013 - Springer
Background Rectal cancer is one of the most prevalent tumor types. Understanding the
metabolic profile of rectal cancer is important for developing therapeutic approaches and …
metabolic profile of rectal cancer is important for developing therapeutic approaches and …
Application of metabolomics to toxicology of drugs of abuse: A mini review of metabolomics approach to acute and chronic toxicity studies
K Zaitsu, Y Hayashi, M Kusano, H Tsuchihashi… - Drug metabolism and …, 2016 - Elsevier
Metabolomics has been widely applied to toxicological fields, especially to elucidate the
mechanism of action of toxicity. In this review, metabolomics application with focus on the …
mechanism of action of toxicity. In this review, metabolomics application with focus on the …
Tissue metabolic profiling of human gastric cancer assessed by 1H NMR
H Wang, H Zhang, P Deng, C Liu, D Li, H Jie, H Zhang… - BMC cancer, 2016 - Springer
Background Gastric cancer is the fourth most common cancer and the second most deadly
cancer worldwide. Study on molecular mechanisms of carcinogenesis will play a significant …
cancer worldwide. Study on molecular mechanisms of carcinogenesis will play a significant …
Forensic NMR metabolomics: one more arrow in the quiver
E Locci, G Bazzano, A Chighine, F Locco, E Ferraro… - Metabolomics, 2020 - Springer
Introduction NMR metabolomics is increasingly used in forensics, due to the possibility of
investigating both endogenous metabolic profiles and exogenous molecules that may help …
investigating both endogenous metabolic profiles and exogenous molecules that may help …
1H-NMR based metabonomic profiling of human esophageal cancer tissue
Background The biomarker identification of human esophageal cancer is critical for its early
diagnosis and therapeutic approaches that will significantly improve patient survival …
diagnosis and therapeutic approaches that will significantly improve patient survival …
Metabolic phenotyping of opioid and psychostimulant addiction: A novel approach for biomarker discovery and biochemical understanding of the disorder
G Caspani, V Sebők, N Sultana… - British Journal of …, 2022 - Wiley Online Library
Despite the progress in characterising the pharmacological profile of drugs of abuse, their
precise biochemical impact remains unclear. The metabolome reflects the multifaceted …
precise biochemical impact remains unclear. The metabolome reflects the multifaceted …
Endogenous opiates and behavior: 2013
RJ Bodnar - Peptides, 2014 - Elsevier
This paper is the thirty-sixth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2013 …
concerning the endogenous opioid system. It summarizes papers published during 2013 …