Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Increasing numbers of individuals suffer from neurodegenerative diseases, which are
characterized by progressive loss of neurons. Oxidative stress, in particular, the …

Taurine is a naturally occurring sulfur-containing amino acid that is found abundantly in
excitatory tissues, such as the heart, brain, retina and skeletal muscles. Taurine was first …

Alzheimer's disease (AD) is the most common progressive human neurodegenerative
disorder affecting elderly population worldwide. Hence, prevention of AD has been a priority …

Objectives The aim of this research was to review the literature on Alzheimer's disease (AD)
with a focus on polyphenolics as antioxidant therapeutics. Design This review included a …

The modern era of drug development for A lzheimer's disease began with the proposal of
the cholinergic hypothesis of memory impairment and the 1984 research criteria for A …

Sumoylation is an essential post‐translational modification intimately involved in a diverse
range of eukaryotic cellular mechanisms. Small ubiquitin‐like modifier (SUMO) protein …

The field of aging and dementia is focusing on the characterization of the earliest stages of
cognitive impairment. Recent research has identified a transitional state between the …

OBJECTIVES: The goal of this study was to project the future prevalence and incidence of
Alzheimer's disease in the United States and the potential impact of interventions to delay …

Herbal medicinals are being used by an increasing number of patients who typically do not
advise their clinicians of concomitant use. Known or potential drug-herb interactions exist …