The default mode network (DMN) is a set of widely distributed brain regions in the parietal,
temporal and frontal cortex. These regions often show reductions in activity during attention …

Nociplastic pain is the semantic term suggested by the international community of pain
researchers to describe a third category of pain that is mechanistically distinct from …

Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

Chronic pain is not simply a temporal continuum of acute pain. Studies on functional
plasticity in neural circuits of pain have provided mechanistic insights and linked various …

Intuition suggests that perception follows sensation and therefore bodily feelings originate in
the body. However, recent evidence goes against this logic: interoceptive experience may …

Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and
unsettling presence in biomedicine. Specifically focused on chronic pain, this review …

Chronic pain is a common public health problem that has a detrimental impact on patient
health, quality of life (QoL), and function, and poses a substantial socioeconomic burden …

Accurate classification of chronic pain conditions requires reliable and valid pain
assessment. Moreover, pain assessment serves several additional functions, including …

It is well-recognized that, despite similar pain characteristics, some people with chronic pain
recover, whereas others do not. In this review, we discuss possible contributions and …

Numerous studies have investigated the impacts of common types of chronic pain (CP) on
patients' cognitive function and observed that CP was associated with later dementia. More …