Natural nonproteinogenic amino acids vastly outnumber the well-known 22 proteinogenic
amino acids. Such amino acids are generated in specialized metabolic pathways. In these …

Biocatalysis fulfils many key criteria of green chemistry, but this raises the question: how
efficient are such production methods and how important is biotechnology for greener …

Transaminases have attracted considerable interest in their use as biocatalysts for the
synthesis of compounds containing chiral amine units, which are widespread within the …

A new method for the decarboxylative coupling of alkyl N-hydroxyphthalimide esters (NHP
esters) with aryl iodides is presented. In contrast to previous studies that form alkyl radicals …

Steric hindrance modification-based pocket reshaping is an effective approach for enzyme–
substrate acceptance evolution. However, previous studies were limited to using the …

Abstract L‐Homophenylalanine (L‐HPA) is a vital building block for the synthesis of
numerous chiral drugs. However, the high cost of starting materials limits the industrial …

Background Direct reductive amination of prochiral 2-oxo-4-phenylbutyric acid (2-OPBA)
catalyzed by phenylalanine dehydrogenase (PheDH) is highly attractive in the synthesis of …

Consumption of tea residues dietary fiber (TRDF) contributed to the relief of hyperglycemia
symptoms in type 2 diabetes (T2D). Given the properties of TRDF abundant in bound …

En la actualidad, existe un enorme deterioro del medio ambiente que ha generado la
necesidad de buscar alternativas que conduzcan a la sostenibilidad ambiental. Una de …

Chemically inert hydrocarbons are the primary feedstocks used in the petrochemical
industry and can be converted into more intricate and valuable chemicals. However, two …