New approaches for targeting platinum-resistant ovarian cancer
M McMullen, A Madariaga, S Lheureux - Seminars in cancer biology, 2021 - Elsevier
Platinum is the backbone of systemic treatment in ovarian cancer and development of
platinum resistance is associated with poor survival. Here, we perform a comprehensive …
platinum resistance is associated with poor survival. Here, we perform a comprehensive …
Platinum-resistant ovarian cancer: From drug resistance mechanisms to liquid biopsy-based biomarkers for disease management
Resistance to platinum-based chemotherapy is a major clinical challenge in ovarian cancer,
contributing to the high mortality-to-incidence ratio. Management of the platinum-resistant …
contributing to the high mortality-to-incidence ratio. Management of the platinum-resistant …
Extracellular microRNAs as intercellular mediators and noninvasive biomarkers of cancer
B Ortiz-Quintero - Cancers, 2020 - mdpi.com
Simple Summary There are an extensive number of publications regarding the role of
endogenous miRNAs as regulators of gene expression in cancer. However, extracellular …
endogenous miRNAs as regulators of gene expression in cancer. However, extracellular …
Liquid biopsies for cancer: From bench to clinic
Over the past two decades, liquid biopsy has been increasingly used as a supplement, or
even, a replacement to the traditional biopsy in clinical oncological practice, due to its …
even, a replacement to the traditional biopsy in clinical oncological practice, due to its …
Extracellular microRNA profiling for prognostic prediction in patients with high‐grade serous ovarian carcinoma
K Yoshida, A Yokoi, J Matsuzaki, T Kato… - Cancer …, 2021 - Wiley Online Library
High‐grade serous ovarian carcinoma is a leading cause of death in female patients
worldwide. MicroRNAs (miRNAs) are stable noncoding RNAs in the peripheral blood that …
worldwide. MicroRNAs (miRNAs) are stable noncoding RNAs in the peripheral blood that …
Role of circulating biomarkers in platinum-resistant ovarian cancer
CM Sassu, I Palaia, SM Boccia, G Caruso… - International Journal of …, 2021 - mdpi.com
Ovarian cancer (OC) is the second most common cause of death in women with
gynecological cancer. Considering the poor prognosis, particularly in the case of platinum …
gynecological cancer. Considering the poor prognosis, particularly in the case of platinum …
[HTML][HTML] The expression and function of miR-622 in a variety of tumors
J Lu, Z Xie, Z Xiao, D Zhu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Cancer is a heavy burden worldwide, with high morbidity and mortality rates. Cancer
treatments currently involve surgical and nonsurgical approaches. Molecular targeted …
treatments currently involve surgical and nonsurgical approaches. Molecular targeted …
Noncoding RNAs interplay in ovarian cancer therapy and drug resistance
M Liu, H Zhang, Y Li, S Wang - Cancer biotherapy & …, 2022 - liebertpub.com
Noncoding RNAs (ncRNAs) are several types of RNA that do not encode proteins, but are
essential for cell regulation. Ovarian cancer (OC) is a type of gynecological cancer with a …
essential for cell regulation. Ovarian cancer (OC) is a type of gynecological cancer with a …
microRNA-622 upregulates cell cycle process by targeting FOLR2 to promote CRC proliferation
Y Chen, F Liu, X Chen, W Li, K Li, H Cai, S Wang… - BMC cancer, 2024 - Springer
Background Epigenetic alterations contribute greatly to the development and progression of
colorectal cancer, and effect of aberrant miR-622 expression is still controversial. This study …
colorectal cancer, and effect of aberrant miR-622 expression is still controversial. This study …
Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors
L Xu, Y Cai, X Chen, Y Zhu, J Cai - BMC cancer, 2021 - Springer
Background Gastrointestinal tumors are a leading cause of mortality worldwide. As shown in
our previous study, miR-1290 is overexpressed in colorectal cancer (CRC) and promotes …
our previous study, miR-1290 is overexpressed in colorectal cancer (CRC) and promotes …