Long non-coding RNAs (lncRNAs) are diverse transcription products emanating from
thousands of loci in mammalian genomes. Cis-acting lncRNAs, which constitute a …

Long noncoding RNAs (lncRNAs) have emerged as important modulators of a wide range of
biological processes in normal and disease states. In particular, lncRNAs have garnered …

Non-coding (nc) RNA plays a vital role in biological processes and has been associated
with diseases such as cancer. Classification of ncRNAs is necessary for understanding the …

Genome-wide association studies indicate that many disease susceptibility regions reside in
non-protein-coding regions of the genome. Long noncoding RNAs (lncRNAs) are a major …

Long non-coding RNAs (lncRNAs) represent a major fraction of the transcriptome in
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …

Chromodomain helicase DNA binding protein 2 (Chd2) is a chromatin remodeller implicated
in neurological disease. Here we show that Chaserr, a highly conserved long noncoding …

Background The genetic basis of variation in the progression of primary tauopathies has not
been determined. We aimed to identify genetic determinants of survival in progressive …

Gene regulatory networks (GRNs) reveal the complex molecular interactions that govern cell
state. However, it is challenging for identifying causal relations among genes due to noisy …

RNA decay is crucial for mRNA turnover and surveillance and misregulated in many
diseases. This complex system is challenging to study, particularly in mammals, where it …

Accurate prediction of gene regulatory rules is important towards understanding of cellular
processes. Existing computational algorithms devised for bulk transcriptomics typically …