Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …

Organoids and organs-on-chips are two rapidly emerging 3D cell culture techniques that
aim to bridge the gap between in vitro 2D cultures and animal models to enable clinically …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

As miniaturized and simplified stem cell-derived 3D organ-like structures, organoids are
rapidly emerging as powerful tools for biomedical applications. With their potential for …

Over the past decade, the emergence of patient-derived tumor organoids (PDTOs) has
broadened the repertoire of preclinical models and progressively revolutionized three …

Immunotherapy as a rapidly developing therapeutic approach has revolutionized cancer
treatment and revitalized the field of tumor immunology research. 3D in vitro models are …

Medicine today faces the combined challenge of an increasing number of untreatable
diseases and fewer drugs reaching the clinic. While pharmaceutical companies have …

Over the past few decades, the enhanced permeability and retention (EPR) effect of
nanomedicine has been a crucial phenomenon in targeted cancer therapy. Specifically …

Simple Summary Pancreatic cancer is one of the most intractable malignant tumors
worldwide, and is known for its refractory and poor prognosis. Pancreatic ductal …

Over the past 15 years, the field of oncology research has witnessed significant progress in
the development of new cell culture models, such as tumor-on-chip (ToC) systems. In this …