Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

Viruses are fully reliant on the translation machinery of their host cells to produce the
polypeptides that are essential for viral replication. Consequently, viruses recruit host …

Viruses are obligate intracellular parasites, and their replication requires host cell functions.
Although the size, composition, complexity, and functions encoded by their genomes are …

Although viruses require cellular functions to replicate, their absolute dependence upon the
host translation machinery to produce polypeptides indispensable for their reproduction is …

Two new vaccines have recently been shown to be safe and effective in protecting young
children against severe rotavirus gastroenteritis. Although both vaccines are now marketed …

Rotaviruses are major causes of acute gastroenteritis in infants and young children
worldwide and also cause disease in the young of many other mammalian and of avian …

The replication of rotavirus is a complex process that is orchestrated by an exquisite
interplay between the rotavirus non-structural and structural proteins. Subsequent to particle …

Early during the infection process, rotavirus causes the shutoff of cell protein synthesis, with
the nonstructural viral protein NSP3 playing a vital role in the phenomenon. In this work, we …

Viral pathogens must overcome innate antiviral responses to replicate successfully in the
host organism. Some of the mechanisms viruses use to interfere with antiviral responses in …

Rotavirus is a segmented double-stranded RNA (dsRNA) virus that causes severe
gastroenteritis in young children. We have established an efficient simplified rotavirus …