Cardiac risk assessment in liver transplant candidates: current controversies and future directions

PM Barman, LB VanWagner - Hepatology, 2021 - Wiley Online Library
In the changing landscape of liver transplantation (LT), we are now evaluating older and
sicker patients with more cardiovascular comorbidities, and the spectrum of cardiovascular …

Ischemic microenvironment‐responsive therapeutics for cardiovascular diseases

X Li, Y Zhang, X Ren, Y Wang, D Chen, Q Li… - Advanced …, 2021 - Wiley Online Library
Cardiovascular diseases caused by ischemia are attracting considerable attention owing to
its high morbidity and mortality worldwide. Although numerous agents with cardioprotective …

Sema7A is crucial for resolution of severe inflammation

A Körner, A Bernard, JC Fitzgerald… - Proceedings of the …, 2021 - National Acad Sciences
Endogenous mediators regulating acute inflammatory responses in both the induction and
resolution phases of inflammatory processes are pivotal in host defense and tissue …

Cellular mechanisms and pathways in myocardial reperfusion injury

I Valikeserlis, AA Athanasiou, D Stakos - Coronary Artery Disease, 2021 - journals.lww.com
Despite the progress of cardiovascular medicine, ischemia-reperfusion injury can contribute
to increased mortality and prolonged hospitalization after myocardial infarction. Ischemia …

[HTML][HTML] Targeting myocardial equilibrative nucleoside transporter ENT1 provides cardioprotection by enhancing myeloid Adora2b signaling

W Ruan, J Li, S Choi, X Ma, Y Liang, R Nair, X Yuan… - JCI insight, 2023 - ncbi.nlm.nih.gov
Previous studies implicate extracellular adenosine signaling in attenuating myocardial
ischemia and reperfusion injury (IRI). This extracellular adenosine signaling is terminated by …

Platelet-derived microRNAs regulate cardiac remodeling after myocardial ischemia

JP Schütte, MC Manke, K Hemmen, P Münzer… - Circulation …, 2023 - Am Heart Assoc
Background: Platelets can infiltrate ischemic myocardium and are increasingly recognized
as critical regulators of inflammatory processes during myocardial ischemia and reperfusion …

Galectin 3 enhances platelet aggregation and thrombosis via Dectin-1 activation: a translational study

Y Chen, W Fu, Y Zheng, J Yang, Y Liu, Z Qi… - European Heart …, 2022 - academic.oup.com
Abstract Aims Galectin-3, a β-galactoside-binding lectin, is abnormally increased in
cardiovascular disease. Plasma Galectin-3 receives a Class II recommendation for heart …

Piperine protects against pyroptosis in myocardial ischaemia/reperfusion injury by regulating the miR‐383/RP105/AKT signalling pathway

X Guo, S Hu, JJ Liu, L Huang, P Zhong… - Journal of Cellular …, 2021 - Wiley Online Library
Abstract miRNA‐mediated pyroptosis play crucial effects in the development of myocardial
ischaemia/reperfusion (I/R) injury (MIRI). Piperine (PIP) possesses multiple pharmacological …

Neuronal guidance genes in health and diseases

J Yuasa-Kawada, M Kinoshita-Kawada, Y Tsuboi… - Protein & …, 2023 - academic.oup.com
Neurons migrate from their birthplaces to the destinations, and extending axons navigate to
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …

PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling

J Li, C Conrad, TW Mills, NK Berg, B Kim… - Journal of Experimental …, 2021 - rupress.org
Previous studies implicated the neuronal guidance molecule netrin-1 in attenuating
myocardial ischemia-reperfusion injury. However, the tissue-specific sources and receptor …