Phage display technology has played a key role in the remarkable progress of discovering
and optimizing antibodies for diverse applications, particularly antibody-based drugs. This …

The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the
resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

mRNA display is a powerful biological display platform for the directed evolution of proteins
and peptides. mRNA display libraries covalently link the displayed peptide or protein …

Following viral infection, viral antigens bind specifically to receptors on the surface of
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …

Immunoassays are reliable, efficient, and accurate methods for the analysis of small‐
molecule harmful substances (such as pesticides, veterinary drugs, and biological toxins) …

This article describes the design of HuCAL (human combinatorial antibody library)
PLATINUM, an optimized, second-generation, synthetic human Fab antibody library with six …

Since the first generation of humanized IgG1 antibodies reached the market in the late
1990s, IgG antibody molecules have been extensively engineered. The success of antibody …

For the past 25 years, phage display technology has been an invaluable tool for studies of
protein–protein interactions. However, the inherent biological, biochemical, and biophysical …

Biocatalysts, especially enzymes, have the ability to catalyze reactions with high product
selectivity, utilize a broad range of substrates, and maintain activity at low temperature and …