[HTML][HTML] Phage display libraries for antibody therapeutic discovery and development
Phage display technology has played a key role in the remarkable progress of discovering
and optimizing antibodies for diverse applications, particularly antibody-based drugs. This …
and optimizing antibodies for diverse applications, particularly antibody-based drugs. This …
[HTML][HTML] In vivo Phage Display: A promising selection strategy for the improvement of antibody targeting and drug delivery properties
AS André, I Moutinho, JNR Dias… - Frontiers in …, 2022 - frontiersin.org
The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the
resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody …
resulting ability to generate monoclonal antibodies (mAbs) initiated a new era in antibody …
[图书][B] Practical handbook of microbiology
LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …
knowledge and practical information about working with microorganisms. Useful to anyone …
Directing evolution of novel ligands by mRNA display
G Kamalinia, BJ Grindel, TT Takahashi… - Chemical Society …, 2021 - pubs.rsc.org
mRNA display is a powerful biological display platform for the directed evolution of proteins
and peptides. mRNA display libraries covalently link the displayed peptide or protein …
and peptides. mRNA display libraries covalently link the displayed peptide or protein …
[HTML][HTML] Massively-multiplexed epitope mapping techniques for viral antigen discovery
D Hu, AT Irving - Frontiers in Immunology, 2023 - frontiersin.org
Following viral infection, viral antigens bind specifically to receptors on the surface of
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …
lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest …
Single‐chain fragment variable produced by phage display technology: Construction, selection, mutation, expression, and recent applications in food safety
L Li, S Wu, Y Si, H Li, X Yin… - Comprehensive Reviews in …, 2022 - Wiley Online Library
Immunoassays are reliable, efficient, and accurate methods for the analysis of small‐
molecule harmful substances (such as pesticides, veterinary drugs, and biological toxins) …
molecule harmful substances (such as pesticides, veterinary drugs, and biological toxins) …
HuCAL PLATINUM, a synthetic Fab library optimized for sequence diversity and superior performance in mammalian expression systems
J Prassler, S Thiel, C Pracht, A Polzer, S Peters… - Journal of molecular …, 2011 - Elsevier
This article describes the design of HuCAL (human combinatorial antibody library)
PLATINUM, an optimized, second-generation, synthetic human Fab antibody library with six …
PLATINUM, an optimized, second-generation, synthetic human Fab antibody library with six …
Engineering the variable region of therapeutic IgG antibodies
T Igawa, H Tsunoda, T Kuramochi, Z Sampei, S Ishii… - MAbs, 2011 - Taylor & Francis
Since the first generation of humanized IgG1 antibodies reached the market in the late
1990s, IgG antibody molecules have been extensively engineered. The success of antibody …
1990s, IgG antibody molecules have been extensively engineered. The success of antibody …
[HTML][HTML] Beyond phage display: non-traditional applications of the filamentous bacteriophage as a vaccine carrier, therapeutic biologic, and bioconjugation scaffold
KA Henry, M Arbabi-Ghahroudi, JK Scott - Frontiers in microbiology, 2015 - frontiersin.org
For the past 25 years, phage display technology has been an invaluable tool for studies of
protein–protein interactions. However, the inherent biological, biochemical, and biophysical …
protein–protein interactions. However, the inherent biological, biochemical, and biophysical …
Engineering novel and improved biocatalysts by cell surface display
Biocatalysts, especially enzymes, have the ability to catalyze reactions with high product
selectivity, utilize a broad range of substrates, and maintain activity at low temperature and …
selectivity, utilize a broad range of substrates, and maintain activity at low temperature and …