Artificial intelligence (AI) has permeated various sectors, including the pharmaceutical
industry and research, where it has been utilized to efficiently identify new chemical entities …

Glutathione (GSH) is a small-molecule thiol that is abundant in all eukaryotes and has key
roles in oxidative metabolism. Mitochondria, as the major site of oxidative reactions, must …

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder
characterized by pathological deposition of misfolded self-protein amyloid beta (Aβ) which in …

Lipid transfer proteins (LTPs) are among the most promising plant-exclusive antimicrobial
peptides (AMPs). They figure among the most challenging AMPs from the point of view of …

The development of bacterial resistance to antibiotics is an increasing public health issue
that worsens with the formation of biofilms. Quorum sensing (QS) orchestrates the bacterial …

Thermostable proteins find their use in numerous biomedical and biotechnological
applications. However, the computational design of stable proteins often results in single …

Background Adeno-associated virus (AAV) vectors are a promising vehicle for noninvasive
gene delivery to the central nervous system via intravenous infusion. However, naturally …

Simple Summary Sodium citrate is a safe and frequently used food additive; the objective of
this study is to assess the effectiveness of sodium citrate at low concentrations of 4% or 5 …

Simple Summary Bacterial infections are considered one of the main challenges to global
health. Bacterial virulence is controlled by interplayed systems to regulate bacterial invasion …

Transfer RNA (tRNA) molecules are essential to decode messenger RNA codons during
protein synthesis. All known tRNAs are heavily modified at multiple positions through post …