Applicability of scrape loading-dye transfer assay for non-genotoxic carcinogen testing

I Sovadinová, BL Upham, JE Trosko… - International Journal of …, 2021 - mdpi.com
Dysregulation of gap junction intercellular communication (GJIC) is recognized as one of the
key hallmarks for identifying non-genotoxic carcinogens (NGTxC). Currently, there is a …

Improved multiparametric scrape loading-dye transfer assay for a simultaneous high-throughput analysis of gap junctional intercellular communication, cell density …

A Dydowiczová, O Brózman, P Babica… - Scientific Reports, 2020 - nature.com
Gap junctional intercellular communication (GJIC) is a vital cellular process required for
maintenance of tissue homeostasis. In vitro assessment of GJIC represents valuable …

Monitoring optoporated process on mammalian cells by real-time measurement of membrane resealing time

X Du, L Fu, Z Wang, Z Zhang, S Jiang… - … of Biomedical Optics, 2023 - spiedigitallibrary.org
Significance Resealing time based loading efficiency of optoporation is the key parameter
for drug or gene delivery. This work describes a comparatively simple optical approach to …

Functionalization of gold-nanoparticles by the Clostridium perfringens enterotoxin C-terminus for tumor cell ablation using the gold nanoparticle-mediated laser …

A Becker, M Leskau, BL Schlingmann-Molina… - Scientific Reports, 2018 - nature.com
A recombinant produced C-terminus of the C. perfringens enterotoxin (C-CPE) was
conjugated to gold nanoparticles (AuNPs) to produce a C-CPE-AuNP complex (C-CPE …

Ablation of red stable transfected claudin expressing canine prostate adenocarcinoma and transitional cell carcinoma cell lines by C-CPE gold-nanoparticle-mediated …

S Alnajjar, I Nolte, A Becker, JT Schille… - International journal of …, 2021 - mdpi.com
Claudin (CLDN) proteins are commonly expressed in cancers and targeted in novel
therapeutic approaches. The C-terminal of Clostridium perfringens enterotoxin (C-CPE) …

Parameters for Optoperforation-Induced Killing of Cancer Cells Using Gold Nanoparticles Functionalized With the C-terminal Fragment of Clostridium Perfringens …

A Becker, T Lehrich, S Kalies, A Heisterkamp… - International journal of …, 2019 - mdpi.com
Recently, we used a recombinant produced C-terminus (D194-F319) of the Clostridium
perfringens enterotoxin (C-CPE) to functionalize gold nanoparticles (AuNPs) for a …

The Bioactive Phenolic Agents Diaryl Ether CVB2-61 and Diarylheptanoid CVB4-57 as Connexin Hemichannel Blockers

A Dierks, C Vanucci-Bacqué, AM Schäfer, T Lehrich… - Pharmaceuticals, 2022 - mdpi.com
Inflammation mediators enhance the activity of connexin (Cx) hemichannels, especially in
the epithelial and endothelial tissues. As potential release routes for injury signals, such as …

The effect of dipyridamole embedded in a drug delivery system made by electrospun nanofibers on aortic endothelial cells

A Repanas, A Bader, A Klett, A Ngezahayo… - Journal of Drug Delivery …, 2016 - Elsevier
An important sector of biomedical research is the generation of drug delivery systems
(DDSs), which can be used alone or integrated in stents for sustained drug release. In this …

Small interfering RNA-mediated connexin gene knockdown in vascular endothelial and smooth muscle cells

ME Good, D Begandt, LJ DeLalio, SR Johnstone… - Gap Junction …, 2016 - Springer
Global knockout of vascular connexins can result in premature/neonatal death, severe
developmental complications, or compensatory up-regulation of different connexin isoforms …

[图书][B] Digitale Bildgebung und Rekonstruktion von lichtbrechenden Proben in den Lebenswissenschaften

GC Antonopoulos - 2016 - repo.uni-hannover.de
Digitale Bildgebung ermöglicht die Darstellung von biologischen Orga-nismen durch
Kombination von physikalischen Messungen und numerischen Rekonstruktionsalgorithmen …