Phlorotannins from brown algae: A review on their antioxidant mechanisms and applications in oxidative stress-mediated diseases
SJ Phang, HX Teh, ML Looi, B Arumugam… - Journal of Applied …, 2023 - Springer
Phlorotannins are polyphenolic compounds that are exclusively derived from marine brown
algae. The molecular structure of phlorotannins with numerous phenol rings endows them …
algae. The molecular structure of phlorotannins with numerous phenol rings endows them …
Insight into the potential application of polyphenol-rich dietary intervention in degenerative disease management
In recent times, a great number of plants have been studied in order to identify new
components with nutraceutical properties, among which are polyphenols. Dietary …
components with nutraceutical properties, among which are polyphenols. Dietary …
Phloroglucinol attenuates DNA damage and apoptosis induced by oxidative stress in human retinal pigment epithelium ARPE-19 cells by blocking the production of …
Phloroglucinol, a phenolic compound, is known to possess a potent antioxidant ability.
However, its role in retinal cells susceptible to oxidative stress has not been well elucidated …
However, its role in retinal cells susceptible to oxidative stress has not been well elucidated …
Formulation and evaluation of SNEDDS loaded with original lipophenol for the oral route to prevent dry AMD and Stragardt's disease
M Vincent, L Simon, P Brabet, P Legrand, C Dorandeu… - Pharmaceutics, 2022 - mdpi.com
Dry age-related macular degeneration (Dry AMD) and Stargardt's disease (STGD1) are
common eye diseases, characterized by oxidative and carbonyl stress (COS)-inducing …
common eye diseases, characterized by oxidative and carbonyl stress (COS)-inducing …
[HTML][HTML] A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration
AK George, M Singh, RP Homme… - International journal …, 2018 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a leading cause of blindness and is becoming a
global crisis since affected people will increase to 288 million by 2040. Genetics, age …
global crisis since affected people will increase to 288 million by 2040. Genetics, age …
Phloroglucinol Inhibits Oxidative-Stress-Induced Cytotoxicity in C2C12 Murine Myoblasts through Nrf-2-Mediated Activation of HO-1
C Park, HJ Cha, H Hwangbo, SY Ji, DH Kim… - International Journal of …, 2023 - mdpi.com
Phloroglucinol is a class of polyphenolic compounds containing aromatic phenyl rings and
is known to have various pharmacological activities. Recently, we reported that this …
is known to have various pharmacological activities. Recently, we reported that this …
New lipophenol antioxidants reduce oxidative damage in retina pigment epithelial cells
E Moine, P Brabet, L Guillou, T Durand, J Vercauteren… - Antioxidants, 2018 - mdpi.com
Age-related macular degeneration (AMD) is a multifactorial pathology and its progression is
exacerbated by oxidative stress. Oxidation and photo-oxidation reactions modify lipids in …
exacerbated by oxidative stress. Oxidation and photo-oxidation reactions modify lipids in …
New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration
E Moine, M Boukhallat, D Cia, N Jacquemot… - Free Radical Biology …, 2021 - Elsevier
Dry age-related macular degeneration and Stargardt disease undergo a known toxic
mechanism caused by carbonyl and oxidative stresses (COS). This is responsible for …
mechanism caused by carbonyl and oxidative stresses (COS). This is responsible for …
Phenotypic high-throughput screening identifies aryl hydrocarbon receptor agonism as common inhibitor of toxin-induced retinal pigment epithelium cell death
J Schustak, H Han, K Bond, Q Huang, M Saint-Geniez… - PloS one, 2024 - journals.plos.org
The retinal pigment epithelium (RPE) is essential to maintain retinal function, and RPE cell
death represents a key pathogenic stage in the progression of several blinding ocular …
death represents a key pathogenic stage in the progression of several blinding ocular …
Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy
N Taveau, A Cubizolle, L Guillou, N Pinquier… - … & Molecular Medicine, 2020 - nature.com
Environmental light has deleterious effects on the outer retina in human retinopathies, such
as ABCA4-related Stargardt's disease and dry age-related macular degeneration. These …
as ABCA4-related Stargardt's disease and dry age-related macular degeneration. These …