The nature of immune responses to urinary tract infections
SN Abraham, Y Miao - Nature Reviews Immunology, 2015 - nature.com
The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …
[HTML][HTML] Gut dysbiosis in animals due to environmental chemical exposures
CS Rosenfeld - Frontiers in cellular and infection microbiology, 2017 - frontiersin.org
The gut microbiome consists of over 103–104 microorganism inhabitants that together
possess 150 times more genes that the human genome and thus should be considered an …
possess 150 times more genes that the human genome and thus should be considered an …
Microbiome disturbances and autism spectrum disorders
CS Rosenfeld - Drug Metabolism and Disposition, 2015 - ASPET
Autism spectrum disorders (ASDs) are considered a heterogenous set of neurobehavioral
diseases, with the rates of diagnosis dramatically increasing in the past few decades. As …
diseases, with the rates of diagnosis dramatically increasing in the past few decades. As …
The immune response to infection in the bladder
L Lacerda Mariano, MA Ingersoll - Nature Reviews Urology, 2020 - nature.com
The bladder is continuously protected by passive defences such as a mucus layer,
antimicrobial peptides and secretory immunoglobulins; however, these defences are …
antimicrobial peptides and secretory immunoglobulins; however, these defences are …
Drug and vaccine development for the treatment and prevention of urinary tract infections
VP O'brien, TJ Hannan, HV Nielsen… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …
Антимикробная терапия и профилактика инфекций почек, мочевыводящих путей и мужских половых органов. Федеральные клинические рекомендации
ТС Перепанова, РС Козлов, ВА Руднов, ЛА Синякова - 2017 - elibrary.ru
Инфекционно-воспалительные урологические осложнения и заболевания
представляют сложную проблему, как для диагностики, так и для лечения. Частота …
представляют сложную проблему, как для диагностики, так и для лечения. Частота …
[HTML][HTML] Immunomodulation therapy offers new molecular strategies to treat UTI
Innovative solutions are needed for the treatment of bacterial infections, and a range of
antibacterial molecules have been explored as alternatives to antibiotics. A different …
antibacterial molecules have been explored as alternatives to antibiotics. A different …
[HTML][HTML] Human microbiota characterization in the course of renal transplantation
Recent studies demonstrate that the human microbiota, the collection of microorganisms
growing on and in individuals, have numerous bidirectional interactions with the host …
growing on and in individuals, have numerous bidirectional interactions with the host …
[HTML][HTML] Innate immunity and genetic determinants of urinary tract infection susceptibility
It is time to start using genetics in UTI-prone patients, to improve diagnosis and to assess the
risk for chronic sequels such as renal malfunction, hypertension, spontaneous abortions …
risk for chronic sequels such as renal malfunction, hypertension, spontaneous abortions …
A bacterial protease depletes c-MYC and increases survival in mouse models of bladder and colon cancer
DSC Butler, C Cafaro, J Putze, MLY Wan… - Nature …, 2021 - nature.com
Is the oncogene MYC upregulated or hyperactive? In the majority of human cancers, finding
agents that target c-MYC has proved difficult. Here we report specific bacterial effector …
agents that target c-MYC has proved difficult. Here we report specific bacterial effector …