Molecular epidemiology, population genetics, and pathogenic role of Helicobacter pylori

R Suzuki, S Shiota, Y Yamaoka - Infection, Genetics and Evolution, 2012 - Elsevier
Helicobacter pylori infection is linked to various gastroduodenal diseases; however, only
approximately 20% of infected individuals develop severe diseases. Despite the high …

The 5300-year-old Helicobacter pylori genome of the Iceman

F Maixner, B Krause-Kyora, D Turaev, A Herbig… - Science, 2016 - science.org
The stomach bacterium Helicobacter pylori is one of the most prevalent human pathogens. It
has dispersed globally with its human host, resulting in a distinct phylogeographic pattern …

Recombination in Bacterial Genomes: Evolutionary Trends

AE Shikov, IA Savina, AA Nizhnikov, KS Antonets - Toxins, 2023 - mdpi.com
Bacterial organisms have undergone homologous recombination (HR) and horizontal gene
transfer (HGT) multiple times during their history. These processes could increase fitness to …

Pectobacterium parvum sp. nov., having a Salmonella SPI-1-like Type III secretion system and low virulence

M Pasanen, M Waleron, T Schott… - … of systematic and …, 2020 - microbiologyresearch.org
Pectobacterium strains isolated from potato stems in Finland, Poland and the Netherlands
were subjected to polyphasic analyses to characterize their genomic and phenotypic …

Discovery of novel mutations for clarithromycin resistance in Helicobacter pylori by using next-generation sequencing

TT Binh, S Shiota, R Suzuki, M Matsuda… - Journal of …, 2014 - academic.oup.com
Objectives Resistance to clarithromycin is the most important factor causing failure of
Helicobacter pylori eradication. Although clarithromycin resistance is mainly associated with …

Helicobacter pylori relies primarily on the purine salvage pathway for purine nucleotide biosynthesis

G Liechti, JB Goldberg - Journal of bacteriology, 2012 - Am Soc Microbiol
Helicobacter pylori is a chronic colonizer of the gastric epithelium and plays a major role in
the development of gastritis, peptic ulcer disease, and gastric cancer. In its coevolution with …

Search for novel candidate mutations for metronidazole resistance in Helicobacter pylori using next-generation sequencing

TT Binh, R Suzuki, TTH Trang, DH Kwon… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Metronidazole resistance is a key factor associated with Helicobacter pylori treatment failure.
Although this resistance is mainly associated with mutations in the rdxA and frxA genes, the …

Network topology analysis of essential genes interactome of Helicobacter pylori to explore novel therapeutic targets

P Gollapalli, H Manjunatha, P Shetty - Microbial Pathogenesis, 2021 - Elsevier
The Helicobacter pylori chronic colonization produces a wide range of gastric diseases in
the gastric mucosa by abetting inflammation. Amidst coevolution and reorganization of its …

Full-genome characterisation of Orungo, Lebombo and Changuinola viruses provides evidence for co-evolution of orbiviruses with their arthropod vectors

F Mohd Jaafar, M Belhouchet, M Belaganahalli… - PLoS …, 2014 - journals.plos.org
The complete genomes of Orungo virus (ORUV), Lebombo virus (LEBV) and Changuinola
virus (CGLV) were sequenced, confirming that they each encode 11 distinct proteins (VP1 …

Comparative genomics of Clavibacter michiganensis subspecies, pathogens of important agricultural crops

JT Tambong - PLoS One, 2017 - journals.plos.org
Subspecies of Clavibacter michiganensis are important phytobacterial pathogens causing
devastating diseases in several agricultural crops. The genome organizations of these …