RNA-Seq technology and its application in fish transcriptomics

X Qian, Y Ba, Q Zhuang, G Zhong - Omics: a journal of integrative …, 2014 - liebertpub.com
High-throughput sequencing technologies, also known as next-generation sequencing
(NGS) technologies, have revolutionized the way that genomic research is advancing. In …

Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research‐practice gaps, challenges, and insights

PP Zheng, J Li, JM Kros - Medicinal research reviews, 2018 - Wiley Online Library
To date, five cancer treatment modalities have been defined. The three traditional modalities
of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two …

Circadian modulation of dopamine levels and dopaminergic neuron development contributes to attention deficiency and hyperactive behavior

J Huang, Z Zhong, M Wang, X Chen, Y Tan… - Journal of …, 2015 - Soc Neuroscience
Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent psychiatric
disorders in children and adults. While ADHD patients often display circadian abnormalities …

Signaling cascades and the importance of moonlight in coral broadcast mass spawning

P Kaniewska, S Alon, S Karako-Lampert… - elife, 2015 - elifesciences.org
Many reef-building corals participate in a mass-spawning event that occurs yearly on the
Great Barrier Reef. This coral reproductive event is one of earth's most prominent examples …

Altered behavioral performance and live imaging of circuit-specific neural deficiencies in a zebrafish model for psychomotor retardation

D Zada, A Tovin, T Lerer-Goldshtein, GD Vatine… - PLoS …, 2014 - journals.plos.org
The mechanisms and treatment of psychomotor retardation, which includes motor and
cognitive impairment, are indefinite. The Allan-Herndon-Dudley syndrome (AHDS) is an X …

Repeated evolution of circadian clock dysregulation in cavefish populations

KL Mack, JB Jaggard, JL Persons, EY Roback… - PLoS …, 2021 - journals.plos.org
Circadian rhythms are nearly ubiquitous throughout nature, suggesting they are critical for
survival in diverse environments. Organisms inhabiting largely arrhythmic environments …

Circadian clocks, rhythmic synaptic plasticity and the sleep-wake cycle in zebrafish

I Elbaz, NS Foulkes, Y Gothilf… - Frontiers in neural circuits, 2013 - frontiersin.org
The circadian clock and homeostatic processes are fundamental mechanisms that regulate
sleep. Surprisingly, despite decades of research, we still do not know why we sleep …

Genetically blocking the zebrafish pineal clock affects circadian behavior

Z Ben-Moshe Livne, S Alon, D Vallone… - PLoS …, 2016 - journals.plos.org
The master circadian clock in fish has been considered to reside in the pineal gland. This
dogma is challenged, however, by the finding that most zebrafish tissues contain molecular …

The light-induced transcriptome of the zebrafish pineal gland reveals complex regulation of the circadian clockwork by light

Z Ben-Moshe, S Alon, P Mracek… - Nucleic acids …, 2014 - academic.oup.com
Light constitutes a primary signal whereby endogenous circadian clocks are synchronized
('entrained') with the day/night cycle. The molecular mechanisms underlying this vital …

Agouti-related protein 2 is a new player in the teleost stress response system

I Shainer, M Michel, GD Marquart, AA Bhandiwad… - Current Biology, 2019 - cell.com
Agouti-related protein (AgRP) is a hypothalamic regulator of food consumption in mammals.
However, AgRP has also been detected in circulation, but a possible endocrine role has not …