Vitronectin (VTN), a multifunctional glycoprotein with various physiological functions, exists
in plasma and the extracellular matrix. It is known to be involved in the cell attachment …

Bone development is characterized by complex regulation mechanisms, including signal
transduction and transcription factor-related pathways, glycobiological processes, cellular …

Background: Renal infiltration of inflammatory cells including macrophages is a crucial event
in kidney fibrogenesis. However, how macrophage regulates fibroblast activation in the …

Suspension TRAPping filter (sTRAP) is an attractive sample preparation method for
proteomics studies. The sTRAP protocol uses 5% SDS that maximizes protein solubilization …

The low sensitivity of nuclear magnetic resonance (NMR) is a major bottleneck for studying
biomolecular structures of complex biomolecular assemblies. Cryogenically cooled probe …

Kidney fibrosis is a common outcome of a wide variety of chronic kidney diseases, in which
virtually all kinds of renal resident and infiltrating cells are involved. As such, well …

The pathogenesis of age-related macular degeneration (AMD), a frequent disorder of the
central retina, is incompletely understood. Genome-wide association studies (GWAS) …

The causes of heart valve bioprosthetic calcification are still not clear. In this paper, we
compared the calcification in the porcine aorta (Ao) and the bovine jugular vein (Ve) walls …

Background Currently, effective therapeutic drugs for age-related macular degeneration
(AMD) are urgently needed, and it is crucial to explore new treatment targets. The proteome …

In this chapter, we will review some of the information regarding the functional significance
of the inorganic phosphate (P i)/pyrophosphate (PP i) ratio for physiological mineralization of …