Mesenchymal stem cells (MSC) exhibit a high self‐renewal capacity, multilineage
differentiation potential and immunomodulatory properties. This set of exceptional features …

Long‐term and stable fixation of implants is one of the most important points for a successful
orthopedic surgery in the field of endoprosthesis. Osseointegration (OI), functional …

Adipose-derived stem cells (ASCs) secrete many cytokines, proteins, growth factors, and
extracellular vesicles with beneficial outcomes that can be used in regenerative medicine. It …

During the last 40 years, there has been a world-wide increase in both the prevalence of
obesity and an increase in the number of persons over the age of 60 due to a decline in …

Advancing age is associated with progressive declines in physiological function that lead to
overt chronic disease, frailty, and eventual mortality. Importantly, age-related physiological …

The mesenchymal stroma harbors an important population of cells that possess stem cell-
like characteristics including self renewal and differentiation capacities and can be derived …

Fat tissue, frequently the largest organ in humans, is at the nexus of mechanisms involved in
longevity and age‐related metabolic dysfunction. Fat distribution and function change …

The potential use of stem cell‐based therapies for the repair and regeneration of various
tissues and organs offers a paradigm shift that may provide alternative therapeutic solutions …

Adipose tissue dysfunction occurs with aging and has systemic effects, including peripheral
insulin resistance, ectopic lipid deposition, and inflammation. Fundamental aging …

Leptin is a hormone discovered almost 30 years ago with important implications in
metabolism. It is primarily produced by white adipose tissue (WAT) in proportion to the …