Already a well-established treatment for different autonomic and movement disorders, the
use of botulinum toxin type A (BoNT/A) in pain conditions is now continuously expanding …

SNARE proteins have been proposed to mediate all intracellular membrane fusion events.
There are over 30 SNARE family members in mammalian cells and each is found in a …

Plasma membrane wounds are repaired by a mechanism involving Ca 2+-regulated
exocytosis. Elevation in intracellular [Ca 2+] triggers fusion of lysosomes with the plasma …

Membrane fusion can occur between cells, between different intracellular compartments,
between intracellular compartments and the plasma membrane and between lipid-bound …

The auditory inner hair cell (IHC) ribbon synapse operates with an exceptional temporal
precision and maintains a high level of neurotransmitter release. However, the molecular …

Regulated exocytosis of secretory granules or dense-core granules has been examined in
many well-characterized cell types including neurons, neuroendocrine, endocrine, exocrine …

Stimulus-secretion coupling is an essential process in secretory cells in which regulated
exocytosis occurs, including neuronal, neuroendocrine, endocrine, and exocrine cells. While …

Neurotransmitter release at synapses involves a highly specialized form of membrane fusion
that is triggered by Ca2+ ions and is optimized for speed. These observations were …

Synaptic vesicle fusion at synapses is triggered by increases in cytosolic Ca 2+ levels.
However, the identity of the Ca 2+ sensor and the transduction mechanism of the Ca 2+ …

Membrane traffic in eukaryotic cells is mediated by transport vesicles that bud from a
precursor compartment and are transported to their destination compartment where they …