MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance
Lung cancer is the cardinal cause of cancer-related deaths with restricted recourse of
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
therapy throughout the world. Clinical success of therapies is not very promising due to-late …
Circular RNAs are miRNA sponges and can be used as a new class of biomarker
Circular RNAs (circRNAs) are a class of non-coding RNAs (ncRNAs) that are involved in
transcriptional and posttranscriptional gene expression regulation. The development of …
transcriptional and posttranscriptional gene expression regulation. The development of …
Circular RNA participates in the carcinogenesis and the malignant behavior of cancer
ZJ Zhao, J Shen - RNA biology, 2017 - Taylor & Francis
Circular RNAs (circRNAs) are long, non-coding RNAs that result from the non-canonical
splicing of linear pre-mRNAs. However, the characteristics and the critical role of circRNA in …
splicing of linear pre-mRNAs. However, the characteristics and the critical role of circRNA in …
CircRNAs and lung cancer: biomarkers and master regulators
X Di, X Jin, R Li, M Zhao, K Wang - Life sciences, 2019 - Elsevier
CircRNAs are a class of competitive, endogenous, non-coding RNAs with closed-loop
structures. High-throughput sequencing indicates that circRNAs are ubiquitously expressed …
structures. High-throughput sequencing indicates that circRNAs are ubiquitously expressed …
Role of microRNAs in regulating cell proliferation, metastasis and chemoresistance and their applications as cancer biomarkers in small cell lung cancer
M Pandey, A Mukhopadhyay, SK Sharawat… - Biochimica et Biophysica …, 2021 - Elsevier
Small cell lung cancer (SCLC), a smoking-related highly aggressive neuroendocrine cancer,
is characterized by rapid cell proliferation, early metastatic dissemination, and early relapse …
is characterized by rapid cell proliferation, early metastatic dissemination, and early relapse …
DNA damage response regulation by microRNAs as a therapeutic target in cancer
M Majidinia, B Yousefi - DNA repair, 2016 - Elsevier
The inability of cancer cells in taking care of DNA damages can lead to cancer development
and/or progression. Due to the essential role of DNA repair in maintaining genomic stability …
and/or progression. Due to the essential role of DNA repair in maintaining genomic stability …
Progress in research on the role of circular RNAs in lung cancer
Y Chen, S Wei, X Wang, X Zhu, S Han - World journal of surgical oncology, 2018 - Springer
Abstract Background Circular RNA (circRNA), as a covalently closed circular RNA molecule,
is widely present, which is recognized as a competing endogenous RNA. A large number of …
is widely present, which is recognized as a competing endogenous RNA. A large number of …
Targeting DNA damage response in the radio (chemo) therapy of non-small cell lung cancer
L Li, T Zhu, YF Gao, W Zheng, CJ Wang, L Xiao… - International journal of …, 2016 - mdpi.com
Lung cancer is the leading cause of cancer death worldwide due to its high incidence and
mortality. As the most common lung cancer, non-small cell lung cancer (NSCLC) is a terrible …
mortality. As the most common lung cancer, non-small cell lung cancer (NSCLC) is a terrible …
MicroRNAs, DNA damage response, and cancer treatment
M He, W Zhou, C Li, M Guo - International Journal of Molecular Sciences, 2016 - mdpi.com
As a result of various stresses, lesions caused by DNA-damaging agents occur constantly in
each cell of the human body. Generally, DNA damage is recognized and repaired by the …
each cell of the human body. Generally, DNA damage is recognized and repaired by the …
Polyphenols as lung cancer chemopreventive agents by targeting microRNAs
J Li, X Zhong, Y Zhao, J Shen, C Pilapong, Z Xiao - Molecules, 2022 - mdpi.com
Lung cancer is the second leading cause of cancer-related death worldwide. In recent
decades, investigators have found that microRNAs, a group of non-coding RNAs, are …
decades, investigators have found that microRNAs, a group of non-coding RNAs, are …