The 5′ and 3′ untranslated regions (UTRs) regulate crucial aspects of post-transcriptional
gene regulation that are necessary for the maintenance of cellular homeostasis. When these …

Alternative polyadenylation (APA), a phenomenon that RNA molecules with different 3′
ends originate from distinct polyadenylation sites of a single gene, is emerging as a …

Understanding gene expression and regulation requires insights into RNA transcription,
processing, modification, and translation. However, the relationship between the …

The obesity rate is rapidly increasing, which has been attributed to lack of exercise and
excessive energy intake. Here, we found a previously unidentified explanation, due to lack …

The tremendous rate with which data is generated and analysis methods emerge makes it
increasingly difficult to keep track of their domain of applicability, assumptions, limitations …

Background Sarcolipin and uncoupling protein 3 (UCP3) mediate muscle-based non-
shivering thermogenesis (NST) to improve metabolic homeostasis. The impacts of maternal …

Although maternal exercise (ME) becomes increasingly uncommon, the effects of ME on
offspring muscle metabolic health remain largely undefined. Maternal mice are subject to …

Obesity's complex etiology due to the interplay of environment and genetics makes it a more
challenging research and health problem. Some of the contributing genetic factors that have …

The seventh iteration of the reference genome assembly for Rattus norvegicus—mRatBN7.
2—corrects numerous misplaced segments and reduces base-level errors by approximately …

Background The accurate identification of the functional elements in the bovine genome is a
fundamental requirement for high-quality analysis of data informing both genome biology …