The structure and pharmacological functions of coumarins and their derivatives

L Wu, X Wang, W Xu, F Farzaneh… - Current medicinal …, 2009 - ingentaconnect.com
Coumarins are of many different structures. They constitute an important class of
pharmacological agents possessing a range of different physiological activities including …

NFκB: a promising target for natural products in cancer chemoprevention

S Luqman, JM Pezzuto - Phytotherapy Research, 2010 - Wiley Online Library
The transcription factor nuclear factor kappa B (NFκB) is found in nearly all animal cell types.
It is involved in cellular responses to stimuli such as stress, cytokines, free radicals …

Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of β-defensin 2 via TLR2 and TLR4

S Gariboldi, M Palazzo, L Zanobbio… - The Journal of …, 2008 - journals.aai.org
In sites of inflammation or tissue injury, hyaluronic acid (HA), ubiquitous in the extracellular
matrix, is broken down into low mw HA (LMW-HA) fragments that have been reported to …

Synthesis and anti-inflammatory effects of a series of novel 7-hydroxycoumarin derivatives

JM Timonen, RM Nieminen, O Sareila, A Goulas… - European journal of …, 2011 - Elsevier
A number of 7-hydroxycoumarins have been synthesised by Pechmann cyclisation using
differently substituted resorcinols employing perchloric acid as the condensing agent. All the …

[HTML][HTML] Antioxidant and anti-inflammatory activities of broccoli florets in LPS-stimulated RAW 264.7 cells

JH Hwang, SB Lim - Preventive nutrition and food science, 2014 - ncbi.nlm.nih.gov
Broccoli (Brassica oleracea var. italia) florets were extracted with 80% methanol and the
extract was sequentially fractionated with n-hexane, ethyl acetate, n-butanol, and distilled …

[HTML][HTML] Preparation and in vivo evaluation of nano sized cubosomal dispersion loaded with Ruta graveolens extracts as a novel approach to reduce asthma-mediated …

MH Alyami, DI Hamdan, HMA Khalil, MAA Orabi… - Saudi Pharmaceutical …, 2024 - Elsevier
Asthma is a chronic disease affecting people of all ages. Asthma medications are associated
with adverse effects restricting their long-term usage, demanding newer alternative …

Synthesis, biological evaluation and molecular docking studies of 3-(triazolyl)-coumarin derivatives: Effect on inducible nitric oxide synthase

HA Stefani, K Gueogjan, F Manarin, SHP Farsky… - European journal of …, 2012 - Elsevier
A series of 3-(triazolyl)-coumarins were synthesized and tested as anti-inflammatory agents.
It was possible to infer that these compounds do not alter the interaction of LPS with TLR-4 …

[PDF][PDF] Ethnobotanical study of medicinal plants in urban home gardens in the city of Abaetetuba, Pará state, Brazil

IC Palheta, ACC Tavares-Martins, FCA Lucas… - … Latinoamericano y del …, 2017 - redalyc.org
This was an ethnobotanical study of medicinal plants occurring in home gardens in the
northern Brazilian Pará state. We conducted semi-structured interviews with the owners of …

Evaluation of inhibitory activities of plant extracts on production of LPS-stimulated pro-inflammatory mediators in J774 murine macrophages

N Verma, SK Tripathi, D Sahu, HR Das… - Molecular and cellular …, 2010 - Springer
Whole plant methanolic extracts of 14 traditionally used medicinal herbs were evaluated for
their anti-inflammatory activity. Extracts of Grindelia robusta, Salix nigra, Arnica montana …

Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis

XX Zhu, L Yang, YJ Li, D Zhang, Y Chen… - Pharmacological …, 2013 - Springer
Background In addition to recognized antimalarial effects, Artemisia annua L.(Qinghao)
possesses anticancer properties. The underlying mechanisms of this activity are unknown …